Adipositas - Ursachen, Folgeerkrankungen, Therapie 2023; 17(01): 26-33
DOI: 10.1055/a-1973-8808
Review

Adipositas und Schwangerschaft – Rolle der körperlichen Aktivität

Obesity and Pregnancy – Role of Physical Activity
Nina Ferrari
1   Kölner Zentrum für Prävention im Kindes- und Jugendalter am Herzzentrum der Universitätsklinik Köln, Köln, Deutschland
2   Institut für Bewegungs- und Neurowissenschaft, Abt. Bewegungs- und Gesundheitsförderung, Deutsche Sporthochschule Köln, Köln, Deutschland
,
Christine Joisten
1   Kölner Zentrum für Prävention im Kindes- und Jugendalter am Herzzentrum der Universitätsklinik Köln, Köln, Deutschland
2   Institut für Bewegungs- und Neurowissenschaft, Abt. Bewegungs- und Gesundheitsförderung, Deutsche Sporthochschule Köln, Köln, Deutschland
› Author Affiliations

Zusammenfassung

Körperlicher Aktivität vor als auch während der Schwangerschaft hat zahlreiche positive Effekte auf Mutter und Kind. Allerdings erreichen in Deutschland weniger als die Hälfte der Frauen im Erwachsenenalter die Aktivitätsempfehlungen der Weltgesundheitsorganisation, sich mindestens 150 Minuten in moderater Ausdaueraktivität zu betätigen. In der Schwangerschaft wird die Aktivitätszeit noch weiter reduziert. Kombiniert mit Übergewicht oder Adipositas in der Schwangerschaft hat dies Auswirkungen auf die mütterliche als auch auf die kindliche Gesundheit. Auf Basis der aktuellen Literatur sollen daher beispielhaft die Effekte von Bewegung während der Schwangerschaft auf Mutter und Kind im Kontext Adipositas zusammengestellt sowie die aktuellen Empfehlungen zu Bewegung in dieser Zielgruppe beschrieben werden. Darüber hinaus wird auf die potentiellen zugrundeliegenden Mechanismen eingegangen.

Summary

Physical activity before and during pregnancy has numerous positive effects on both mother and child. However, in Germany, less than half of women in adulthood achieve the World Health Organization’s activity recommendations of at least 150 minutes of moderate endurance activity. During pregnancy, activity time is reduced even further. Combined with overweight or obesity in pregnancy, this has implications for both maternal and fetal health. Therefore, based on the current literature, the effects of exercise during pregnancy on mother and child in the context of obesity will be summarized as an example, and the current recommendations for exercise during pregnancy in this target group will be described. In addition, the potential underlying mechanisms will be addressed.



Publication History

Article published online:
03 March 2023

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  • Literatur

  • 1 Guthold R, Stevens GA, Riley LM. et al. Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 population-based surveys with 1.9 million participants. Lancet Glob Health 2018; 6: e1077-e1086
  • 2 Lange C, Finger J. Gesundheitsverhalten in Europa – Vergleich ausgewählter Indikatoren für Deutschland und die Europäische Union. Journal of Health Monitoring 2017; 2
  • 3 Finger J, Mensink G, Lange C. et al. Gesundheitsfördernde körperliche Aktivität in der Freizeit bei Erwachsenen in Deutschland. Journal of Health Monitoring 2017; 2
  • 4 Gaston A, Cramp A. Exercise during pregnancy: a review of patterns and determinants. Journal of science and medicine in sport/Sports Medicine Australia 2011; 14: 299-305
  • 5 Meander L, Lindqvist M, Mogren I. et al. Physical activity and sedentary time during pregnancy and associations with maternal and fetal health outcomes: an epidemiological study. BMC pregnancy and childbirth 2021; 21: 166
  • 6 Schmidt T, Heilmann T, Savelsberg L. et al. Physical Exercise During Pregnancy – How Active Are Pregnant Women in Germany and How Well Informed?. Geburtshilfe Frauenheilkd 2017; 77: 508-515
  • 7 Bauer C, Graf C, Platschek AM. et al. Reasons, Motivational Factors, and Perceived Personal Barriers to Engagement in Physical Activity During Pregnancy Vary Within the BMI Classes: The Prenatal Prevention Project Germany. J Phys Act Health 2018; 15: 204-211
  • 8 Flanagan EW, Beyl RA, Fearnbach SN. et al. The Impact of COVID-19 Stay-At-Home Orders on Health Behaviors in Adults. Obesity 2021; 29: 438-445
  • 9 Collaboration NCDRF Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet 2017; 390: 2627-2642
  • 10 Janssen F, Bardoutsos A, Vidra N. Obesity Prevalence in the Long-Term Future in 18 European Countries and in the USA. Obes Facts 2020; 13: 514-527
  • 11 Strauss A, Rochow N, Kunze M. et al. Obesity in pregnant women: a 20-year analysis of the German experience. European journal of clinical nutrition 2021; 75: 1757-1763
  • 12 Ferrari N, Mallmann P, Brockmeier K. et al. Secular trends in pregnancy weight gain in German women and their influences on foetal outcome: a hospital-based study. BMC pregnancy and childbirth 2014; 14: 228
  • 13 Marchi J, Berg M, Dencker A. et al. Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews. Obesity reviews: an official journal of the International Association for the Study of Obesity 2015; 16: 621-638
  • 14 Wang Z, Wang P, Liu H. et al. Maternal adiposity as an independent risk factor for pre-eclampsia: a meta-analysis of prospective cohort studies. Obesity reviews: an official journal of the International Association for the Study of Obesity 2013; 14: 508-521
  • 15 Yu Z, Han S, Zhu J. et al. Pre-pregnancy body mass index in relation to infant birth weight and offspring overweight/obesity: a systematic review and meta-analysis. PloS one 2013; 8: e61627
  • 16 Jeffries K, Shub A, Walker SP. et al. Reducing excessive weight gain in pregnancy: a randomised controlled trial. Med J Aust 2009; 191: 429-433
  • 17 Guelinckx I, Devlieger R, Mullie P. et al. Effect of lifestyle intervention on dietary habits, physical activity, and gestational weight gain in obese pregnant women: a randomized controlled trial. The American journal of clinical nutrition 2010; 91: 373-380
  • 18 Asbee SM, Jenkins TR, Butler JR. et al. Preventing excessive weight gain during pregnancy through dietary and lifestyle counseling: a randomized controlled trial. Obstetrics and gynecology 2009; 113: 305-312
  • 19 Skouteris H, Hartley-Clark L, McCabe M. et al. Preventing excessive gestational weight gain: a systematic review of interventions. Obesity reviews : an official journal of the International Association for the Study of Obesity 2010; 11: 757-768
  • 20 Yeo S, Walker JS, Caughey MC. et al. What characteristics of nutrition and physical activity interventions are key to effectively reducing weight gain in obese or overweight pregnant women? A systematic review and meta-analysis. Obesity reviews: an official journal of the International Association for the Study of Obesity 2017; 18: 385-399
  • 21 Bogaerts AF, Devlieger R, Nuyts E. et al. Effects of lifestyle intervention in obese pregnant women on gestational weight gain and mental health: a randomized controlled trial. International journal of obesity 2013; 37: 814-821
  • 22 Vinter CA, Jensen DM, Ovesen P. et al. The LiP (Lifestyle in Pregnancy) study: a randomized controlled trial of lifestyle intervention in 360 obese pregnant women. Diabetes care 2011; 34: 2502-2507
  • 23 Renault KM, Norgaard K, Nilas L. et al. The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. American journal of obstetrics and gynecology 2014; 210: 134 e131-134 e139
  • 24 Muktabhant B, Lawrie TA, Lumbiganon P. et al. Diet or exercise, or both, for preventing excessive weight gain in pregnancy. The Cochrane database of systematic reviews 2015; 15: CD007145
  • 25 Luoto R, Kinnunen TI, Aittasalo M. et al. Primary prevention of gestational diabetes mellitus and large-for-gestational-age newborns by lifestyle counseling: a cluster-randomized controlled trial. PLoS medicine 2011; 8: e1001036
  • 26 Poston L, Bell R, Croker H. et al. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial. Lancet Diabetes Endocrinol 2015; 3: 767-777
  • 27 Dodd JM, Turnbull D, McPhee AJ. et al. Antenatal lifestyle advice for women who are overweight or obese: LIMIT randomised trial. Bmj 2014; 348: g1285
  • 28 Kralisch S, Bluher M, Paschke R. et al. Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome. Mini Rev Med Chem 2007; 7: 39-45
  • 29 Mottola MF, Artal R. Fetal and maternal metabolic responses to exercise during pregnancy. Early human development 2016; 94: 33-41
  • 30 Fakhraei R, Denize K, Simon A. et al. Predictors of Adverse Pregnancy Outcomes in Pregnant Women Living with Obesity: A Systematic Review. International journal of environmental research and public health 2022; 19
  • 31 Thagaard IN, Hedley PL, Holm JC. et al. Leptin and Adiponectin as markers for preeclampsia in obese pregnant women, a cohort study. Pregnancy Hypertens 2019; 15: 78-83
  • 32 Steell L, Ho FK, Sillars A. et al. Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study. Br J Sports Med 2019; 53: 1371-1378
  • 33 Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 2008; 454: 463-469
  • 34 Pedersen BK, Akerstrom TC, Nielsen AR. et al. Role of myokines in exercise and metabolism. Journal of applied physiology 2007; 103: 1093-1098
  • 35 Rodriguez A, Becerril S, Ezquerro S. et al. Crosstalk between adipokines and myokines in fat browning. Acta Physiol (Oxf) 2017; 219: 362-381
  • 36 Thyfault JP, Bergouignan A. Exercise and metabolic health: beyond skeletal muscle. Diabetologia 2020; 63: 1464-1474
  • 37 Goudreau AD, Everest C, Nagpal TS. et al. Elucidating the interaction between maternal physical activity and circulating myokines throughout gestation: A scoping review. American journal of reproductive immunology 2021; 86: e13488
  • 38 van Poppel MN, Peinhaupt M, Eekhoff ME. et al. Physical activity in overweight and obese pregnant women is associated with higher levels of proinflammatory cytokines and with reduced insulin response through interleukin-6. Diabetes care 2014; 37: 1132-1139
  • 39 Golbidi S, Laher I. Potential mechanisms of exercise in gestational diabetes. J Nutr Metab 2013; 2013: 285948
  • 40 Bae-Gartz I, Janoschek R, Kloppe CS. et al. Running Exercise in Obese Pregnancies Prevents IL-6 Trans-signaling in Male Offspring. Medicine and science in sports and exercise 2016; 48: 829-838
  • 41 Acosta-Manzano P, Coll-Risco I, Van Poppel MNM. et al. Influence of a Concurrent Exercise Training Intervention during Pregnancy on Maternal and Arterial and Venous Cord Serum Cytokines: The GESTAFIT Project. J Clin Med 2019; 8
  • 42 [Anonym] Physical Activity and Exercise During Pregnancy and the Postpartum Period: ACOG Committee Opinion Summary, Number 804. Obstetrics and gynecology 2020; 135: 991-993
  • 43 Mottola MF, Davenport MH, Ruchat SM. et al. No. 367-2019 Canadian Guideline for Physical Activity throughout Pregnancy. J Obstet Gynaecol Can 2018; 40: 1528-1537
  • 44 [Anonym]. In WHO Guidelines on Physical Activity and Sedentary Behaviour. Geneva; 2020
  • 45 Mottola MF. Physical activity and maternal obesity: cardiovascular adaptations, exercise recommendations, and pregnancy outcomes. Nutr Rev 2013; 71: S31-S36
  • 46 Conway MR, Marshall MR, Schlaff RA. et al. Physical Activity Device Reliability and Validity during Pregnancy and Postpartum. Medicine and science in sports and exercise 2018; 50: 617-623
  • 47 Kominiarek MA, Vyhmeister H, Balmert LC. et al. Activity Tracking Devices in Group Prenatal Care: A Feasibility Study. Biores Open Access 2018; 7: 165-176
  • 48 Artal R, Masaki DI, Khodiguian N. et al. Exercise prescription in pregnancy: weight-bearing versus non-weight-bearing exercise. American journal of obstetrics and gynecology 1989; 161: 1464-1469
  • 49 Drenowatz C, Hand GA, Shook RP. et al. The association between different types of exercise and energy expenditure in young nonoverweight and overweight adults. Applied physiology, nutrition, and metabolism=Physiologie appliquee, nutrition et metabolisme 2015; 40: 211-217
  • 50 Newton ER, May L. Adaptation of Maternal-Fetal Physiology to Exercise in Pregnancy: The Basis of Guidelines for Physical Activity in Pregnancy. Clin Med Insights Womens Health 2017; 10: 1179562X17693224
  • 51 Katz VL, McMurray R, Berry MJ. et al. Fetal and uterine responses to immersion and exercise. Obstetrics and gynecology 1988; 72: 225-230
  • 52 Nieuwenhuijsen MJ, Northstone K, Golding J. et al. Swimming and birth weight. Epidemiology 2002; 13: 725-728
  • 53 Juhl M, Kogevinas M, Andersen PK. et al. Is swimming during pregnancy a safe exercise. Epidemiology 2010; 21: 253-258
  • 54 Lynch AM, McDonald S, Magann EF. et al. Effectiveness and safety of a structured swimming program in previously sedentary women during pregnancy. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstet 2003; 14: 163-169
  • 55 Evenson KR, Barakat R, Brown WJ. et al. Guidelines for Physical Activity during Pregnancy: Comparisons From Around the World. Am J Lifestyle Med 2014; 8: 102-121
  • 56 Barakat R, Lucia A, Ruiz JR. Resistance exercise training during pregnancy and newborn’s birth size: a randomised controlled trial. International journal of obesity 2009; 33: 1048-1057
  • 57 Petrov Fieril K, Glantz A, Fagevik Olsen M. The efficacy of moderate-to-vigorous resistance exercise during pregnancy: a randomized controlled trial. Acta obstetricia et gynecologica Scandinavica 2015; 94: 35-42
  • 58 Barakat R, Perales M. Resistance Exercise in Pregnancy and Outcome. Clinical obstetrics and gynecology 2016; 59: 591-599
  • 59 Mottola MF, Davenport MH, Ruchat SM. et al. 2019 Canadian guideline for physical activity throughout pregnancy. Br J Sports Med 2018; 52: 1339-1346
  • 60 Ibrahim S, Jarefors E, Nel DG. et al. Effect of maternal position and uterine activity on periodic maternal heart rate changes before elective cesarean section at term. Acta obstetricia et gynecologica Scandinavica 2015; 94: 1359-1366
  • 61 Avery ND, Stocking KD, Tranmer JE. et al. Fetal responses to maternal strength conditioning exercises in late gestation. Can J Appl Physiol 1999; 24: 362-376
  • 62 Jeffreys RM, Stepanchak W, Lopez B. et al. Uterine blood flow during supine rest and exercise after 28 weeks of gestation. BJOG : an international journal of obstetrics and gynaecology 2006; 113: 1239-1247
  • 63 [Anonym] . ACOG Committee Opinion No. 650: Physical Activity and Exercise During Pregnancy and the Postpartum Period. Obstetrics and gynecology 2015; 126: e135-e142
  • 64 McAuliffe FM, Killeen SL, Jacob CM. et al. Management of prepregnancy, pregnancy, and postpartum obesity from the FIGO Pregnancy and Non-Communicable Diseases Committee: A FIGO (International Federation of Gynecology and Obstetrics) guideline. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2020; 151: 16-36
  • 65 Denison FC, Weir Z, Carver H. et al. Physical activity in pregnant women with Class III obesity: A qualitative exploration of attitudes and behaviours. Midwifery 2015; 31: 1163-1167
  • 66 Baillot A, Chenail S, Barros Polita N. et al. Physical activity motives, barriers, and preferences in people with obesity: A systematic review. PloS one 2021; 16: e0253114
  • 67 O’Keeffe LM, Dahly DL, Murphy M. et al. Positive lifestyle changes around the time of pregnancy: a cross-sectional study. BMJ Open 2016; 6: e010233
  • 68 Flannery C, McHugh S, Anaba AE. et al. Enablers and barriers to physical activity in overweight and obese pregnant women: an analysis informed by the theoretical domains framework and COM-B model. BMC pregnancy and childbirth 2018; 18: 178
  • 69 Lindhardt CL, Rubak S, Mogensen O. et al. Healthcare professionals experience with motivational interviewing in their encounter with obese pregnant women. Midwifery 2015; 31: 678-684
  • 70 Landgraf R, Kellerer M, Aberle J. et al. Therapie des Typ-2 Diabetes. Diabetologie und Stoffwechsel 2018; 13: S144-S165