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Endoscopy 2023; 55(06): 557-562
DOI: 10.1055/a-2013-1902
Innovations and brief communications

No-touch endoscopic full-thickness resection technique for gastric gastrointestinal stromal tumors

Tao Chen‡   ‡
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Yun-Wei Zhang‡   ‡
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Jing-Jing Lian
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Hai-Bin Zhang
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Ai-Ping Xu
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Fang Li
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Xiao-Han Yan
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Ben-Song Duan
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Zi-Ying Zhao
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Yuan Chu 
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Li Shen
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Jia Cao
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Li Zhang
2   Department of Pathology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Liang Zheng
3   Research Center for Translation Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Shu-Guang Chu
4   Department of Radiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
,
Mei-Dong Xu
1   Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
› Author Affiliations
Supported by: The Top-level Clinical Discipline Project of Shanghai Pudong PWYgf2021–2 Supported by: Shanghai Committee of Science and Technology 19411951505
› Further Information
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Comments on “No-touch endoscopic full-thickness resection technique for gastric gastrointestinal stromal tumors”Endoscopy 2024; 56(01): 80-81
DOI: 10.1055/a-2147-0456

Abstract

Background There remain concerns regarding the technical feasibility of endoscopic resection for large gastrointestinal stromal tumors (GISTs), mainly relating to the risk of tumor rupture and the adequacy of the resection margins. This study aimed to evaluate the feasibility and therapeutic outcomes of the newly developed no-touch endoscopic full-thickness resection (NT-EFTR) technique for GISTs.

Methods In this retrospective study, 92 patients with gastric GISTs undergoing NT-EFTR were included. Clinicopathological, endoscopic, and follow-up data were collected and analyzed.

Results The median tumor size was 2.5 cm and en bloc resection was achieved in all patients with negative surgical margins. The median time of the NT-EFTR procedure was 59.5 minutes. Large tumors (> 3.0 cm), extraluminal tumor growth pattern, and large gastric defects were significant contributors to long operative times. Patients were discharged within 4 days postoperatively. During follow-up, all patients were free from local recurrence and distant metastasis.

Conclusions NT-EFTR was a feasible method for the resection of gastric GISTs and can be expected to achieve complete radical resection. Large tumors with extraluminal growth and large gastric defects impact procedural difficulty.

‡ These authors contributed equally to this paper.


Tables 1 s–3 s, Figs. 1 s–3 s



Publication History

Received: 04 April 2022

Accepted after revision: 22 November 2022

Article published online:
09 February 2023

© 2023. Thieme. All rights reserved.

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