Hyperfibrinolyse nach Reanimation bei akuter Lungenarterienembolie

Zusammenfassung

Kommt es nach einer Reanimation – z. B. wegen akuter Lungenarterienembolie – im Rahmen eines Post-Cardiac-Arrest-Syndroms (PCAS) zu einer Hyperfibrinolyse, stellt dies eine diagnostische und therapeutische Herausforderung dar. In diesem Fallbericht wird die Pathophysiologie der Koagulopathie bei PCAS beschrieben und der Einsatz antifibrinolytischer Therapie bei Patienten mit thrombotischen Komplikationen wie Lungenarterienembolien diskutiert.

Abstract

Hyperfibrinolysis which can occur in the context of a post-cardiac arrest syndrome (PCAS) after resuscitation – e.g. due to acute pulmonary artery embolism – poses a diagnostic and therapeutic challenge.This case report describes the pathophysiology of coagulopathy in PCAS and discusses the viscoelastometrically monitored use of antifibrinolytic therapy in patients with thrombotic complications such as pulmonary artery embolism.

Schlüsselwörter

disseminierte intravasale Gerinnung - Lungenarterienembolie - Hyperfibrinolyse - Tranexamsäure - Post-Cardiac-Arrest-Syndrom

Keywords

disseminated intravascular coagulation - pulmonary artery embolism - hyperfibrinolysis - tranexamic acid - post-cardiac arrest syndrome

Publication History

Article published online:
08 May 2024

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