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DOI: 10.1055/a-2333-9480
Congenital gastric ectopic pylorus: a rare gastric malformation
Supported by: National Key Research and Development Project 2022YFC2503603
A 71-year-old man who presented with hematemesis and melena was admitted to our hospital. He denied any previous surgery history or recent use of alcohol and antithrombotic agents. Esophagogastroduodenoscopy (EGD) revealed an opening leading to the duodenum and the blind antrum without normal pylorus ([Fig. 1],[Fig. 2]). The ectopic pyloric opening was located in the lesser curvature of the upper gastric body, approximately 2 cm distal to the cardia. Multiple ulcers were also found near the opening without active bleeding ([Video 1]). The upper gastroenterography and computed tomography showed the teapot-like stomach, further confirming the ectopic pyloric opening in the upper gastric body ([Fig. 3],[Fig. 4]). With conservative medication, the patient gained a rapid recovery and was discharged uneventfully.








Congenital gastric ectopic pylorus is an extremely rare congenital gastric abnormality, which was first reported and coined by Yu ZL et al. [1] in 1983. Uraz S et al. [2] published the first English literature in 2007. This disease occurs more frequently in the 6th and 7th decade of life, with a male predominance (8:1). The majority of reported cases (89.2%) were from East Asia, and the underlying mechanism remained unknown. Most patients present non-specific symptoms, such as abdominal pain, bloating, regurgitation, and belching. However, almost 30% of patients may manifest with upper gastrointestinal bleeding. With continuous acid reflux from the stomach to the duodenum, the constantly open ectopic pylorus may contribute to peptic ulcers and subsequent bleeding [3]. We should improve our understanding of this disease to avoid misdiagnosis.
Endoscopy_UCTN_Code_TTT_1AO_2AB
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Conflict of Interest
The authors declare that they have no conflict of interest.
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References
- 1 Yu ZL, Zhao ZY. Gastric ectopic pylorus: a case report. Chin J Pract Intern Med 1983; 3: 321
- 2 Uraz S, Aygün C, Konduk T. et al. A rare gastric outlet anomaly: pyloric ostium on incissura angularis. Dig Dis Sci 2007; 52: 1001-1003
- 3 Calhan T, Sahin A, Kahraman R. et al. Atypical placement of the pylorus: a rare congenital abnormality. Endoscopy 2014; 46: E302-E303
Correspondence
Publication History
Article published online:
12 June 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
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References
- 1 Yu ZL, Zhao ZY. Gastric ectopic pylorus: a case report. Chin J Pract Intern Med 1983; 3: 321
- 2 Uraz S, Aygün C, Konduk T. et al. A rare gastric outlet anomaly: pyloric ostium on incissura angularis. Dig Dis Sci 2007; 52: 1001-1003
- 3 Calhan T, Sahin A, Kahraman R. et al. Atypical placement of the pylorus: a rare congenital abnormality. Endoscopy 2014; 46: E302-E303







