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DOI: 10.1055/a-2563-9069
Evaluation of the Effectiveness and Safety of Telemedicine in Rheumatoid Arthritis: Meta-analysis
Funding This study was supported by the Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China (grant number: 81860882).

Abstract
Objectives
This study aimed to systematically evaluate the effectiveness and safety of telemedicine in improving the corresponding indicators in patients with rheumatoid arthritis (RA).
Methods
Computer searches of PubMed, Embase, the Cochrane Library, and Web of Science were conducted to collect journal articles on randomized controlled trials and clinical trials of telemedicine interventions for RA. A meta-analysis was performed using the risk-of-bias assessment tool Reedman 5.4 software from the Cochrane Handbook.
Results
The systematic assessment includes 17 studies totaling 2,324 patients, with a middling level of quality across the included research. The findings of this study demonstrated that individuals with RA had better treatment efficiency in C-reactive protein than those in the control group (mean difference [MD] = − 21.17, 95% confidence interval [CI] = − 49.57 to 7.23; p < 0.00001), Rheumatoid Arthritis Quality of Life (MD = − 1.97, 95% CI = − 6.13 to 2.19; p = 0.01), and visual analog scale pain (MD = − 8.53, 95% CI = − 22.70 to 5.64; p = 0.04).
Conclusion
Patients with RA can access specialists worldwide through telemedicine, which can raise the overall quality of care for RA patients. It has shown to be quite successful in identifying and evaluating disease activity. By making patient-centeredness a central factor in the decision-making process, telemedicine improves equitable results and offers customized treatment regimens.
Protection of Human and Animal Subjects
All analyses were based on previous published studies; thus, no ethical approval and patient consent are required.
Publication History
Received: 11 November 2024
Accepted: 20 March 2025
Article published online:
23 July 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
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