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Int J Angiol
DOI: 10.1055/a-2631-5355
Review Article

Aneurysmal Coronary Artery Disease: A Contemporary and Comprehensive Review

Mohamad Mubder 
1   University Medical Center, Las Vegas, Nevada
,
Noyan Ramazani
2   Department of Medicine, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas, Nevada
,
Vasiliki Tasouli-Drakou
2   Department of Medicine, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas, Nevada
,
Nazanin Houshmand
2   Department of Medicine, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas, Nevada
,
Tahir Tak 
2   Department of Medicine, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas, Nevada
3   Veterans Administration Southern Nevada Healthcare System, Department of Cardiovascular Medicine, North Las Vegas, Nevada
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Funding None.
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Abstract

Coronary artery aneurysm (CAA) is a focal enlargement of the coronary artery exceeding 1.5 times the diameter of the adjacent normal segment of the vessel. The reported prevalence of CAA varies widely from 0.2 to 10%, with male predominance and a predilection for the right coronary artery. Atherosclerosis is the main cause in adults and Kawasaki disease in children. While often asymptomatic, CAA may present with angina, myocardial infarction, or possible fatal complications such as rupture, compression of adjacent cardiopulmonary structures, thrombus formation, and distal embolization. CAA is usually an incidental finding during coronary angiography; however, advancements in cardiac imaging have enhanced the detection and characterization of CAA. Coronary computed tomography angiography and magnetic resonance angiography offer alternatives to traditional approaches with high-resolution images that can help with risk stratification and management planning. Management varies based on the size, location, complications, and presence of symptoms. It includes medical therapy, percutaneous intervention, and surgical approach. In this paper, we aim to provide a comprehensive review of current knowledge of CAA and recent advances in its diagnosis and management.

Keywords

coronary artery aneurysm - coronary artery ectasia - giant coronary artery aneurysm - Kawasaki disease - coronary artery dilatation - coronary artery thrombosis


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Artikel online veröffentlicht:
01. Juli 2025

© 2025. International College of Angiology. This article is published by Thieme.

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