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DOI: 10.1055/a-2644-7982
Removal of lollipop-shaped stent-stone complex using direct-vision laser lithotripsy
Supported by: Science and Technology Innovation Plan of Science and Technology Commission of Shanghai Municipality, China 22Y11909000
Long-term retention of biliary plastic stents (PS) can lead to a rare complication: the formation of a lollipop-shaped stent-stone complex (LSSC) [1], where stones encase the proximal end of the stent, making endoscopic removal technically difficult. We report a case of successful LSSC removal using peroral cholangioscopy (POCS)-guided frequency-doubled dual pulse Nd:YAG (FREDDY) laser lithotripsy.
A 72-year-old man, previously diagnosed with IgG4-related sclerosing cholangitis, underwent biliary and pancreatic PS placement three years prior to alleviate obstructive jaundice ([Fig. 1]), followed by corticosteroid therapy. He was lost to follow-up. One month before admission, he presented with jaundice and fever. Emergency ERCP showed resolution of the biliary stricture but revealed a retained LSSC in the common bile duct (CBD). Removal attempts using standard tools failed, fracturing the stent at the duodenal lumen. A supplementary PS was placed to ensure drainage ([Fig. 2]). Following stabilization, repeat ERCP was performed using POCS-guided laser lithotripsy. The PS was fully encased in yellow stones, forming an LSSC. FREDDY laser lithotripsy (U-100 Plus; World of Medicine, Berlin, Germany) was applied at the stent-stone interface under direct visualization to fragment the stones and gradually release the stent. The stent was successfully removed, and residual stones were cleared ([Fig. 3], [Video 1]). The patient recovered well and was discharged three days later.






LSSC formation is associated with long-term stent retention (≥301 days) and CBD dilation [2]. The potential for LSSC formation should be considered in patients with long-term PS indwelling and dilated CBD. Endoscopic LSSC removal is technically challenging: standard endoscopic tools may fail, and forcible extraction risks ductal injury and perforation. Extracorporeal shock wave lithotripsy is technically complex [3], while surgical intervention is traumatic. FREDDY laser lithotripsy is safer than Ho:YAG laser and electrohydraulic lithotripsy [4] [5]. POCS-guided FREDDY laser lithotripsy offers a safe, minimally invasive, and effective approach for LSSC management.
Removal of lollipop-shaped stent-stone complex using direct-vision laser lithotripsy.Video 1Endoscopy_UCTN_Code_CPL_1AK_2AF
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Conflict of Interest
The authors declare that they have no conflict of interest.
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References
- 1 Tang SJ, Armstrong L, Lara LF. et al. De novo stent-stone complex after long-term biliary stent placement: pathogenesis, diagnosis, and endotherapy. Gastrointest Endosc 2007; 66: 193-200
- 2 Kaneko J, Kawata K, Watanabe S. et al. Clinical characteristics and risk factors for stent-stone complex formation following biliary plastic stent placement in patients with common bile duct stones. J Hepatobiliary Pancreat Sci 2018; 25: 448-454
- 3 Manes G, Paspatis G, Aabakken L. et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy 2019; 51: 472-491
- 4 Veld JV, van Huijgevoort NCM, Boermeester MA. et al. A systematic review of advanced endoscopy-assisted lithotripsy for retained biliary tract stones: laser, electrohydraulic or extracorporeal shock wave. Endoscopy 2018; 50: 896-909
- 5 Ni ZK, Jin HM, Li XW. et al. Combination of Electronic Choledochoscopy and Holmium Laser Lithotripsy for Complicated Biliary Calculus Treatment: A New Exploration. Surg Laparosc Endosc Percutan Tech 2018; 28: e68-e73
Correspondence
Publication History
Article published online:
29 July 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
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References
- 1 Tang SJ, Armstrong L, Lara LF. et al. De novo stent-stone complex after long-term biliary stent placement: pathogenesis, diagnosis, and endotherapy. Gastrointest Endosc 2007; 66: 193-200
- 2 Kaneko J, Kawata K, Watanabe S. et al. Clinical characteristics and risk factors for stent-stone complex formation following biliary plastic stent placement in patients with common bile duct stones. J Hepatobiliary Pancreat Sci 2018; 25: 448-454
- 3 Manes G, Paspatis G, Aabakken L. et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy 2019; 51: 472-491
- 4 Veld JV, van Huijgevoort NCM, Boermeester MA. et al. A systematic review of advanced endoscopy-assisted lithotripsy for retained biliary tract stones: laser, electrohydraulic or extracorporeal shock wave. Endoscopy 2018; 50: 896-909
- 5 Ni ZK, Jin HM, Li XW. et al. Combination of Electronic Choledochoscopy and Holmium Laser Lithotripsy for Complicated Biliary Calculus Treatment: A New Exploration. Surg Laparosc Endosc Percutan Tech 2018; 28: e68-e73





