PDF herunterladen
Semin Liver Dis
DOI: 10.1055/a-2677-3773
Review Article

Endohepatology in the Management of Liver Diseases

Authors

  • Thomas J. Wang

    1   Division of Digestive Diseases and Nutrition, Center for Interventional and Therapeutic Endoscopy, Rush University Medical Center, Chicago, Illinois
    2   Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, California

  • Ajaypal Singh

    1   Division of Digestive Diseases and Nutrition, Center for Interventional and Therapeutic Endoscopy, Rush University Medical Center, Chicago, Illinois
Weitere Informationen
   Lizenzen und Reprints


Graphical Abstract

Preview

Abstract

Endohepatology is an emerging field that encompasses various diagnostic and therapeutic endoscopic ultrasound (EUS) techniques for the management of liver disease. It encompasses diagnostic techniques for fibrosis staging and portal hypertension evaluation, as well as therapeutic interventions for conditions like variceal bleeding. Given the medical complexity and fragility that are often encountered in patients with liver disease, careful attention is of paramount importance to minimize risk and invasiveness when possible while extracting maximal value with a therapeutic intent. EUS-guided access to liver, bile ducts, and the hepatic vasculature provides the ability for diagnostic evaluation and interventions, which are not limited by body habitus and the need for central vascular access. Established EUS-guided techniques include liver biopsy, direct portal pressure gradient measurements, and gastric variceal coiling and injection therapies. More emerging techniques, including liver palpation, shear wave elastography, portal venous sampling, rectal variceal coiling, and partial splenic artery embolization, have also been described in the literature. This review details the rationale and evidence behind both established and emerging EUS-guided techniques, highlighting their current and potential future impact on endohepatology.

Keywords

diagnostic and therapeutic EUS - EUS-based techniques - portal hypertension - variceal bleeding - liver fibrosis evaluation


Publikationsverlauf

Artikel online veröffentlicht:
29. August 2025

© 2025. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA