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DOI: 10.1055/a-2706-3220
A case in which all stones, including gallbladder stones as well as stacked bile duct stones, were removed using a transpapillary procedure
Authors
The guidelines for the treatment of choledocholithiasis recommend that cholecystectomy should be performed after endoscopic removal of stones in the common bile duct (CBD) in cases with gallbladder stones [1] [2], but we report here on a case in which all stones in the CBD, intrahepatic bile duct, and gallbladder were removed through the papilla.
A 76-year-old man visited his previous doctor with nausea. He was diagnosed with acute cholangitis due to a large, stacked-type bile duct stone that had blocked the left and right intrahepatic bile ducts ([Fig. 1]). However, the stone was difficult to remove, and he was referred to our hospital.


First, we performed an endoscopic sphincterotomy combined with large-balloon dilation using a disposable balloon dilator. We then removed the distal bile duct stone using a stone removal balloon. Electrohydraulic lithotripsy was performed using a cholangioscope for the large stone at the cystic duct bifurcation. Then, we successfully removed giant stones at the confluence of the gallbladder ducts ([Fig. 2]). As the cystic duct was large and a guidewire was successfully inserted, the stone was crushed using a stone-crushing basket, and a plastic stent was placed. In the re-treatment, endoscopic papillary large-balloon dilation was performed using a papilla dilation balloon, and the intrahepatic bile duct stone was removed using a balloon catheter. The stone at the bottom of the gallbladder remained, but the rotating basket (RASEN-2; Kaneka Medix, Osaka, Japan) was guided into the gallbladder, and the stone at the bottom of the gallbladder was removed ([Video 1]). The cholangiogram confirmed that the stone had been completely removed.


Stones in the biliary tract can be removed entirely by transpapillary procedures. If the cystic duct is thick and straight, we might also attempt to remove the gallbladder stones.
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Conflict of Interest
The authors declare that they have no conflict of interest.
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References
- 1 Boerma D, Rauws EA, Keulemans Y. et al. Wait and see policy or laparoscopic cholecystectomy after endoscopic sphincterotomy for bile duct stones: a randomized trial. Lancet 2002; 360: 761-765
- 2 Fujita N, Yasuda I, Endo I. et al. Evidence-based clinical practice guidelines for cholelithiasis 2021. J Gastroenterol 2023; 58: 801-833
Correspondence
Publication History
Article published online:
21 October 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
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References
- 1 Boerma D, Rauws EA, Keulemans Y. et al. Wait and see policy or laparoscopic cholecystectomy after endoscopic sphincterotomy for bile duct stones: a randomized trial. Lancet 2002; 360: 761-765
- 2 Fujita N, Yasuda I, Endo I. et al. Evidence-based clinical practice guidelines for cholelithiasis 2021. J Gastroenterol 2023; 58: 801-833




