Subscribe to RSS
DOI: 10.1055/a-2776-3877
Das leise Risiko: Einsamkeit und Gesundheit
The Silent Risk: Loneliness and HealthAuthors
Zusammenfassung
Einsamkeit hat stark an wissenschaftlicher und gesundheitspolitischer Relevanz gewonnen. Sie zeigt ein U-förmiges Muster über die Lebensspanne und betrifft besonders vulnerable Gruppen. Ihre Entstehung beruht auf einem Zusammenspiel individueller, relationaler und sozialräumlich-struktureller Faktoren. Längsschnitt- und Metaanalysen belegen klare Zusammenhänge mit psychischen Störungen, kardiometabolischen Erkrankungen, kognitiven Beeinträchtigungen und erhöhter Mortalität. Zugleich kann Einsamkeit durch gezielte Interventionen reduziert werden. Die Nutzung generativer KI als emotionale Begleitung wirft zusätzliche ethische und psychosoziale Fragen auf. Insgesamt bleibt Einsamkeit ein zentraler sozialer Risikofaktor, der integrierte, mehrstufige Maßnahmen erfordert.
Abstract
Loneliness has gained significant scientific and public health relevance. Prevalence follows a U-shaped pattern across the life course, with especially high rates in vulnerable groups. Its emergence reflects an interplay of individual, relational, community and structural factors. Longitudinal evidence links loneliness consistently to depression, anxiety, suicidality, cardiometabolic disease, cognitive decline and mortality. Targeted interventions can reduce loneliness, though the growing use of generative AI as emotional support introduces ethical and psychosocial concerns. Overall, loneliness is a key socially rooted risk factor that requires integrated, multi-level strategies for effective prevention and reduction.
Schlüsselwörter
Einsamkeit - soziale Isolation - soziale Determinanten - Gesundheit - Public Mental HealthPublication History
Received: 24 November 2025
Accepted after revision: 18 December 2025
Article published online:
23 February 2026
© 2026. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
-
Literatur
- 1 World Health Organization. From loneliness to social connection: charting a path to healthier societies. Report of the WHO Commission on Social Connection. Im Internet: https://www.who.int/publications/i/item/978240112360 Stand: 17.11.2025
- 2 Zhang Y, Kuang J, Xin Z. et al. Loneliness, social isolation, depression and anxiety among the elderly in Shanghai: Findings from a longitudinal study. Arch Gerontol Geriatr 2023; 110: 104980
- 3 Valtorta NK, Kanaan M, Gilbody S. et al. Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart 2016; 102: 1009-1016
- 4 Surkalim DL, Luo M, Eres R. et al. The prevalence of loneliness across 113 countries: systematic review and meta-analysis. BMJ 2022; 376: e067068
- 5 Röhr S, Wittmann F, Engel C. et al. Social factors and the prevalence of social isolation in a population-based adult cohort. Soc Psychiatry Psychiatr Epidemiol 2022; 57: 1959-1968
- 6 Graham EK, Beck ED, Jackson K. et al. Do We Become More Lonely With Age? A Coordinated Data Analysis of Nine Longitudinal Studies. Psychol Sci 2024; 35: 579-596
- 7 Moormann KI, Pabst A, Bleck F. et al. Social isolation in the oldest-old: determinants and the differential role of family and friends. Soc Psychiatry Psychiatr Epidemiol 2024; 59: 979-988
- 8 Luhmann M, Buecker S, Rüsberg M. Loneliness across time and space. Nat Rev Psychol 2023; 2: 9-23
- 9 Ernst M, Niederer D, Werner AM. et al. Loneliness before and during the COVID-19 pandemic: A systematic review with meta-analysis. Am Psychol 2022; 77: 660-677
- 10 Hajek A, Gyasi RM, Pengpid S. et al. Prevalence of loneliness and social isolation amongst individuals with severe mental disorders: a systematic review and meta-analysis. Epidemiol Psychiatr Sci 2025; 34: e25
- 11 Morrish N, Medina-Lara A. Does unemployment lead to greater levels of loneliness? A systematic review. Soc Sci Med 2021; 287: 114339
- 12 Holt-Lunstad J. Why Social Relationships Are Important for Physical Health: A Systems Approach to Understanding and Modifying Risk and Protection. Annu Rev Psychol 2018; 69: 437-458
- 13 Terracciano A, Luchetti M, Karakose S. et al. Personality traits and loneliness: An ecological momentary assessment study with self and partner ratings. J Res Pers 2025; 116
- 14 Lykes VA, Kemmelmeier M. What Predicts Loneliness? Cultural Difference Between Individualistic and Collectivistic Societies in Europe. Journal of Cross-Cultural Psychology 2014; 45: 468-490
- 15 Kunz JS, Trinh T-A, Berk M. et al. Are recessions bad for loneliness. Soc Sci Med 2025; 384: 118500
- 16 Holt-Lunstad J, Smith TB, Baker M. et al. Loneliness and social isolation as risk factors for mortality: a meta-analytic review. Perspect Psychol Sci 2015; 10: 227-237
- 17 Nakou A, Dragioti E, Bastas N-S. et al. Loneliness, social isolation, and living alone: a comprehensive systematic review, meta-analysis, and meta-regression of mortality risks in older adults. Aging Clin Exp Res 2025; 37: 29
- 18 Mann F, Wang J, Pearce E. et al. Loneliness and the onset of new mental health problems in the general population. Soc Psychiatry Psychiatr Epidemiol 2022; 57: 2161-2178
- 19 McClelland H, Evans JJ, Nowland R. et al. Loneliness as a predictor of suicidal ideation and behaviour: a systematic review and meta-analysis of prospective studies. J Affect Disord 2020; 274: 880-896
- 20 Albasheer O, Abdelwahab SI, Zaino MR. et al. The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation. Sci Rep 2024; 14: 12871
- 21 Hackett RA, Hudson JL, Chilcot J. Loneliness and type 2 diabetes incidence: findings from the English Longitudinal Study of Ageing. Diabetologia 2020; 63: 2329-2338
- 22 Lara E, Martín-María N, La Torre-Luque Ade. et al. Does loneliness contribute to mild cognitive impairment and dementia? A systematic review and meta-analysis of longitudinal studies. Ageing Res Rev 2019; 52: 7-16
- 23 Fan K, Seah B, Lu Z. et al. Association between loneliness and mild cognitive impairment in older adults: a meta-analysis of longitudinal studies. Aging Ment Health 2024; 28: 1650-1658
- 24 Mahalingam G, Samtani S, Lam BCP. et al. Social connections and risk of incident mild cognitive impairment, dementia, and mortality in 13 longitudinal cohort studies of ageing. Alzheimers Dement 2023; 19: 5114-5128
- 25 Lammer L, Beyer F, Luppa M. et al. Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study. Elife 2023; 12
- 26 Park C, Majeed A, Gill H. et al. The Effect of Loneliness on Distinct Health Outcomes: A Comprehensive Review and Meta-Analysis. Psychiatry Res 2020; 294: 113514
- 27 Mann F, Bone JK, Lloyd-Evans B. et al. A life less lonely: the state of the art in interventions to reduce loneliness in people with mental health problems. Soc Psychiatry Psychiatr Epidemiol 2017; 52: 627-638
- 28 Duffner LA, Janssen N, Deckers K. et al. Facing the Next „Geriatric Giant“-A Systematic Literature Review and Meta-Analysis of Interventions Tackling Loneliness and Social Isolation Among Older Adults. J Am Med Dir Assoc 2024; 25: 105110
- 29 Gühne U, Weinmann S, Prestin E. et al. S3-Leitlinie „Psychosoziale Therapien bei schweren psychischen Erkrankungen“ 3.0 – Wege zu Recovery. Psychiat Prax 2025; 52: 413-415
- 30 Koschig M, Müller M, Röhrig J. et al. Sportvereine als Setting der psychischen Gesundheitsförderung bei Kindern und Jugendlichen. Psychiat Prax 2025; 52: 258-264
- 31 Bundesministerium für Familie, Senioren, Frauen und Jugend. Strategie der Bundesregierung gegen Einsamkeit (Dezember 2023). Im Internet: https://www.bmbfsfj.bund.de/resource/blob/234584/9c0557454d1156026525fe67061e292e/2023-strategie-gegen-einsamkeit-data.pdf Stand: 13.11.2025
- 32 Zao-Sanders M. How People are Really Using Generative AI Now. Filtered Report on the Top 100 Generative AI Use Cases. Im Internet: https://learn.filtered.com/hubfs/The%202025%20Top-100%20Gen%20AI%20Use%20Case%20Report.pdf Stand: 13.11.2025
- 33 Hajek A, Zwar L, Gyasi RM. et al. Association of using AI tools for personal conversation with social disconnectedness outcomes. J Public Health (Berl.) 2025;
- 34 Maples B, Cerit M, Vishwanath A. et al. Loneliness and suicide mitigation for students using GPT3-enabled chatbots. Npj Ment Health Res 2024; 3: 4
- 35 Kim M, Lee S, Kim S. et al. Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study. J Med Internet Res 2025; 27: e65589
- 36 Fang CM, Liu AR, Danry V, Lee E, Chan SWT, Pataranutaporn P, Maes P, Phang J, Lampe M, Ahmad L, Agarwal S. How AI and Human Behaviors Shape Psychosocial Effects of Extended Chatbot Use: A Longitudinal Randomized Controlled Study. [Preprint]. Im Internet: https://arxiv.org/pdf/2503.17473 Stand: 17.11.2025
- 37 Smith MG, Bradbury TN, Karney BR. Can Generative AI Chatbots Emulate Human Connection? A Relationship Science Perspective. Perspect Psychol Sci 2025; 20: 1081-1099
- 38 Schreiter S. Digital Health in der Psychiatrie – Potentiale und Risiken. Psychiat Prax 2024; 51: 347-350
- 39 Figueroa JF, Jha AK. Polysocial Risk Scores for Assessing Social Determinants of Health-Reply. JAMA 2020; 324: 1681-1682
- 40 Chen S, Chen S, Hanewald K. et al. Social Environment, Lifestyle, and Genetic Predisposition With Dementia Risk: A Long-Term Longitudinal Study Among Older Adults. J Gerontol A Biol Sci Med Sci 2024; 79
- 41 Koschig M, Riedel-Heller SG. Die Förderung psychischer Gesundheit und Primärprävention psychischer Störungen – ein Zukunftsthema. Psychiat Prax 2024; 51: 407-409
