Zusammenfassung
Omega-3-Fettsäuren (FS) Eicosapentaensäure (EPA) und Docosahexaensäure (DHA) sind
wichtige Bestandteile der Nahrung. Gegenwärtig ist jedoch die Aufnahme dieser essenziellen
mehrfach ungesättigten Fettsäuren im Rahmen der täglichen Ernährung unzureichend.
Es soll daher darauf geachtet werden, dass EPA und DHA dem Organismus in ausreichender
Menge, vor allem in Form von Fisch und Fischprodukten, zugeführt werden. Wird eine
optimale Versorgung des Körpers durch die normale Nahrungszufuhr nicht sichergestellt,
können Supplementationsmöglichkeiten überlegt werden. In der vorliegenden Arbeit wird
der Stellenwert von Omega-3-FS für Prävention und Therapie unterschiedlicher Erkrankungen
sowie ihre Wirkmechanismen diskutiert. Es wird weiter auf die praktischen Verfahren
eingegangen, den individuellen Omega-3-Status zu bestimmen und durch unterschiedliche
Maßnahmen eine ausreichende Zufuhr von Omega-3-FS zu gewährleisten.
Abstract
Omega-3 fatty acids (FA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
are important components of nutrition. Unfortunately, the intake of these essential
polyunsaturated fatty acids is often insufficient in western countries. Therefore,
it is of particular importance, that the organism receives adequate amounts of EPA
and DHA from nourishment (fish and fish products). If the optimal intake of Omega-3
FA from nutrition can not be achieved in an individual, supplementation should be
considered. In the present review, the role of Omega-3 fatty acids in prevention and
therapy of various diseases, as well as their mechanisms of action, are discussed.
Furthermore, the paper addresses practical options to determine the individual Omega-3
status and describes different possibilities to assure sufficient intake of Omega-3
FA.
Schlüsselwörter
Omega-3-Fettsäuren - Prävention - Therapie - Eicosapentaensäure - Docosahexaensäure
Key words
Omega-3 fatty acids - prevention - therapy - eicosapentaenoic acid - docosahexaenoic
acid
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Evgeny Idelevich
Institut für Klinische Pharmakologie, Medizinische Fakultät, Technische Universität
Dresden
Fiedlerstraße 27
01307 Dresden
Email: evgeny.idelevich@tu-dresden.de