Exp Clin Endocrinol Diabetes 2009; 117(7): 350-353
DOI: 10.1055/s-0029-1220689
Article

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Prevalence of Diabetes and Cardiovascular Risk Factors of Industrial Area in Southern Poland

A. Wittek 1 , B. Sokalski 1 , W. Grzeszczak 2 , K. Strojek 2
  • 1Outpatient Clinic for Diabetics Ruda Slaska, Silesian Medical University Zabrze, Poland
  • 2Department of Internal Diseases Diabetology and Nephrology, Silesian Medical University Zabrze, Poland
Further Information

Publication History

received 14.06.2008 first decision 05.08.2008

accepted 09.10.2008

Publication Date:
17 June 2009 (online)

Abstract

Background: Diabetes mellitus (DM) is a serious health and social problem. We assessed the prevalence of DM and metabolic syndrome in an urban population in southern Poland.

Methods: Sample of 782 subjects randomly selected from adult inhabitants of industrial district (23 442 voters registered) was invited. The response rate was 56% (including 85% of those aged over 50 years) mean age 53±15 years. 75 g OGTT and serum concentration of triglycerides, total cholesterol and HDL/LDL fractions were measured. The percentage±assessment error for the disorders were calculated assuming not-responders represented normal glucose tolerance.

Results: Prevalence of DM was 8.06±0.9% (7.15±1.25 M and 8.94±1.3 F) including 5.56±0.77% (5.56±1.13 M and 5.56±1.06 F) with known and 2.52±0.55 (1.59±0.64 M and 3.37±0.89 F) newly diagnosed. Impaired glucose tolerance (IGT and/or IFG) was found in additional 8.44±0.93% (6.09±1.17 M and 10.7±1.41 F). Extrapolated to the general population shown the prevalence 6.54±0.73% (5.8±1.02 M and 7.25±1.05 F). Features of the metabolic syndrome (IDF criteria) were found in 34% of the participants – 75% of patients with DM, 63% with glucose intolerance (IGT and/or IFG) and 19% of individuals with NGT (p<0.001 as compared to other groups).

Conclusions The study confirmed high prevalence of diabetes mellitus with lower percentage of undiagnosed disease. Presence of impaired glucose tolerance allows to identify the high risk of metabolic syndrome and in consequence high risk of cardiovascular disease.

References

  • 1 Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic.  Nature. 2001;  414 782-787
  • 2 King H, Aubert RE, Herman WH. Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections.  Diabetes Care. 1998;  21 1414-1431
  • 3 Wild S, Roglic G, Green A. et al . Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.  Diabetes Care. 2004;  27 1047-1053
  • 4 King H, Rewers M. Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults.  WHO Ad Hoc Diabetes Reporting Group. Diabetes Care. 1993;  16 157-177
  • 5 Harris MI, Klein R, Welborn TA. et al . Onset of NIDDM occurs at least 4–7 yr before diagnosis.  Diabetes Care. 1992;  15 815-819
  • 6 Stratton IM, Adler AI, Andrew H. et al . Association of glycaemia with microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.  BMJ. 2000;  321 405-412
  • 7 Expert Committee on the diagnosis and classification of diabetes mellitus Report . Diabetes Care. 1997;  20 1183-1197
  • 8 World Health Organization .Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of a WHO Consultation. Geneva: World Health Organization 1999
  • 9 Reaven GM. Role of insulin resistance in human disease.  Diabetes. 1988;  37 1595-1607
  • 10 UK Prospective Diabetes Study (UKPDS) Group . Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33).  Lancet. 1998;  352 837-853
  • 11 Central Statistical Office (Glówny Urząd Statystyczny) . Warszawa. 2005;  http://www.stat.gov.pl/demografia/index.html
  • 12 Screening for Type 2 Diebetes, Report of a World Health Organization and International Diabetes Federation meeting .Departament of Noncommunicable Disease Management. Geneva 2003
  • 13 Beaglehole R, Bonita R, Kielström S. Basic epidemiology. WHO Genewa 1993
  • 14 The IDF consensus worldwide definition of the metabolic syndrome http://www.idf.org 2005; 
  • 15 Cowie CC, Rust KF, Byrd-Holt DD. et al . Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U.S. Population: National Health and Nutrition Examination Survey 1999–2002.  Diabetes Care. 2006;  29 1263-1268
  • 16 Sieradzki J, Wilkins A, Szczepañski M. SCREEN-POL 2 – active screening and early diagnosis of type 2 diabetes In patients admitted to primary care in Poland (in Polish).  Diabetologia Praktyczna. 2005;  6 103-114
  • 17 Hauner H, Hanisch J, Bramlage P. et al . Prevalence of undiagnosed type-2-diabetes mellitus and impaired fasting glucose in German primary care: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS).  Exp Clin Endocrinol Diabetes. 2008;  116 18-25
  • 18 Kannel WB, MacGee DL. Diabetes and cardiovascular disease: the Framingham study.  JAMA. 1979;  241 2035-2038
  • 19 Klein BEK, Klein R, Lee KE. Components of metabolic syndrome and risk of cardiovascular disease and diabetes in beaver dam.  Diabetes Care. 2002;  25 1790-1794
  • 20 Kahn R, Buse J, Ferrannini E. et al . American Diabetes Association; European Association for the Study of Diabetes. The metabolic syndrome: time for a critical appraisal: joint statement from American Diabetes Association and the European Association for the Study of Diabetes.  Diabetes Care. 2005;  285 2486-2497

Correspondence

Prof. K. Strojek

Department of Internal Diseases Diabetology and Nephrology

Silesian Medical University

3-Maja 13/15

41-800 Zabrze

Poland

Phone: 4832/271 25 11

Fax: 4832/271 66 91

Email: kstrojek@sum.edu.pl

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