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Endo-Praxis 2011; 27(2): e4-e9
DOI: 10.1055/s-0031-1278001
Neue Behandlungsmethoden

© Georg Thieme Verlag Stuttgart · New York

Endomikroskopie

M. Goetz1 , R. Kiesslich1
  • 1I. Medizinische Klinik und Poliklinik, Universitätsmedizin Mainz
Further Information

Publication History

Publication Date:
24 May 2011 (online)

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Die konfokale Endomikroskopie ist eine neuartige endo-skopische Technologie, die die Videoendoskopie mit der intravitalen Mikroskopie verbindet und eine mikroskopische Betrachtung der gastrointestinalen Mukosa in Echtzeit (während der laufenden Endoskopie) erlaubt.

Schlüsselwörter

Endomikroskopie - in vivo Mikroskopie - konfokale Bildgebung

Literatur

Literatur

  • 1 Kudo S, Tamura S, Nakajima T et al.. Diagnosis of colorectal tumorous lesions by magnifying endoscopy.  Gastrointest Endosc. 1996;  44 8-14
    CrossrefPubMedGoogle Scholar
  • 2 Dunbar KB, Montgomery EA, Canto MI. The Learning Curve of In Vivo Confocal Laser Endomicroscopy for Prediction of Barrett's Esophagus.  Gastroenterology. 2008;  134
    Google Scholar
  • 3 Kiesslich R, Burg J, Vieth M et al.. Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo.  Gastroenterology. 2004;  127 706-713
    CrossrefPubMedGoogle Scholar
  • 4 Wallace MB, Meining A, Canto MI et al.. Review article: safety of intravenous fluorescein for confocal laser endomicroscopy in the gastrointestinal tract.  Aliment Pharmacol Ther. 2010;  31 548-552
    CrossrefGoogle Scholar
  • 5 Polglase AL, McLaren WJ, Skinner SA et al.. A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract.  Gastrointest Endosc. 2005;  62 686-695
    CrossrefPubMedGoogle Scholar
  • 6 Goetz M, Toermer T, Vieth M et al.. Simultaneous confocal laser endomicroscopy and chromoendoscopy with topical cresyl violet.  Gastrointest Endosc. 2009;  70 959-968
    CrossrefGoogle Scholar
  • 7 Kiesslich R, Gossner L, Goetz M et al.. In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy.  Clin Gastroenterol Hepatol. 2006;  4 979-987
    CrossrefPubMedGoogle Scholar
  • 8 Pohl H, Rosch T, Vieth M et al.. Miniprobe confocal laser microscopy for the detection of invisible neoplasia in patients with Barrett's oesophagus.  Gut. 2008;  57 1648-1653
    CrossrefGoogle Scholar
  • 9 Dunbar KB, Okolo 3rd P, Montgomery E et al.. Confocal laser endomicroscopy in Barrett's esophagus and endoscopically inapparent Barrett's neoplasia: a prospective, randomized, double-blind, controlled, crossover trial.  Gastrointest Endosc. 2009;  70 645-654
    CrossrefGoogle Scholar
  • 10 Deinert K, Kiesslich R, Vieth M et al.. In-vivo microvascular imaging of early squamous-cell cancer of the esophagus by confocal laser endomicroscopy.  Endoscopy. 2007;  39 366-368
    Article in Thieme ConnectGoogle Scholar
  • 11 Pech O, Rabenstein T, Manner H et al.. Confocal laser endomicroscopy for in vivo diagnosis of early squamous cell carcinoma in the esophagus.  Clin Gastroenterol Hepatol. 2008;  6 89-94
    CrossrefGoogle Scholar
  • 12 Li WB, Zuo XL, Zuo F et al.. Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy.  Surg Endosc. 2010;  24 517-524
    CrossrefGoogle Scholar
  • 13 Zhang JN, Li YQ, Zhao YA et al.. Classification of gastric pit patterns by confocal endomicroscopy.  Gastrointest Endosc. 2008;  67 843-853
    CrossrefGoogle Scholar
  • 14 Kiesslich R, Goetz M, Burg J et al.. Diagnosing Helicobacter pylori in vivo by confocal laser endoscopy.  Gastroenterology. 2005;  128 2119-2123
    CrossrefPubMedGoogle Scholar
  • 15 Guo YT, Li YQ, Yu T et al.. Diagnosis of gastric intestinal metaplasia with confocal laser endomicroscopy in vivo: a prospective study.  Endoscopy. 2008;  40 547-553
    Article in Thieme ConnectGoogle Scholar
  • 16 Kitabatake S, Niwa Y, Miyahara R et al.. Confocal endomicroscopy for the diagnosis of gastric cancer in vivo.  Endoscopy. 2006;  38 1110-1114
    Article in Thieme ConnectPubMedGoogle Scholar
  • 17 Leong RW, Nguyen NQ, Meredith CG et al.. In vivo confocal endomicroscopy in the diagnosis and evaluation of celiac disease.  Gastroenterology. 2008;  135 1870-1876
    CrossrefGoogle Scholar
  • 18 Kiesslich R, Goetz M, Lammersdorf K et al.. Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis.  Gastroenterology. 2007;  132 874-882
    CrossrefPubMedGoogle Scholar
  • 19 Kiesslich R, Hoffman A, Goetz M et al.. In vivo diagnosis of collagenous colitis by confocal endomicroscopy.  Gut. 2006;  55 591-592
    CrossrefPubMedGoogle Scholar
  • 20 Zambelli A, Villanacci V, Buscarini E et al.. Collagenous colitis: a case series with confocal laser microscopy and histology correlation.  Endoscopy. 2008;  40 606-608
    Article in Thieme ConnectGoogle Scholar
  • 21 Bojarski C, Gunther U, Rieger K et al.. In vivo diagnosis of acute intestinal graft-versus-host disease by confocal endomicroscopy.  Endoscopy. 2009;  41 433-438
    Article in Thieme ConnectGoogle Scholar
  • 22 Kiesslich R, Goetz M, Angus EM et al.. Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy.  Gastroenterology. 2007;  133 1769-1778
    CrossrefGoogle Scholar
  • 23 Hsiung PL, Hardy J, Friedland S et al.. Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy.  Nat Med. 2008;  14 454-458
    CrossrefGoogle Scholar
  • 24 Goetz M, Ziebart A, Foersch S et al.. In vivo molecular imaging of colorectal cancer with confocal endomicroscopy of epidermal growth factor receptor.  Gastroenterology. 2010;  138 453-446
    Google Scholar

Korrespondenzadresse

Univ.-Prof. Dr. Ralf Kiesslich

I. Medizinische Klinik und Poliklinik Johannes Gutenberg-Universität Mainz

Langenbeckstr. 1

55131 Mainz

Email: kiesslich@uni-mainz.de

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