Immunthrombozytopenie

Schlüsselwörter

Immunthrombozytopenie - Thrombopoietin-Rezeptorantagonisten - Romiplostim - Rituximab - Splenektomie

Keywords

immune thrombocytopenia - thrombopoietin receptor agonists - romiplostim - rituximab - splenectomy

Literatur

• 1 Emmons R BV, Reid D M, Cohen R L. et al . Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.  Blood. 1996;  87 4068-4071
• 2 Godeau B, Porcher R, Fain O. et al . Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura – results of a prospective multicenter phase 2 study.  Blood. 2008;  112 999-1004
• 3 Kuter D J. New thrombopoietic growth factors.  Blood. 2007;  109 4607-4616
• 4 Kuter D J, Rummel M, Boccia R. et al . Romiplostim or standard of care in patients wtih immune thrombocytopenia.  N Engl J Med. 2010;  363 1889-1899
• 5 Matzdorff A, Giagounidis A, Greinacher A. et al . Diagnostik und Therapie der Immunthrombozytopenie. Empfehlungen einer gemeinsamen Expertengruppe der DGHO, DGTI und GTH.  Onkologie. 2010;  33 (Suppl 3) 2-20
• 6 Neunert C, Lim W, Crowther M, Cohen A, Solberg L, Crowther M. Clinical guideline update on „Immune Thrombocytopenia: an evidence based practice guideline developed by the American Society of Hematology”.  Blood. 2011;  e-pub ahead of print
• 7 Provan D, Stasi R, Newland A C. et al . International consensus report on the investigation and management of primary immune thrombocytopenia.  Blood. 2010;  115 168-196
• 8 Rodeghiero F, Stasi R, Gernsheimer T. et al . Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: Report from an International Working Group.  Blood. 2009;  113 2386-2393
• 9 Zaja F, Baccarani M, Mazza P. et al . Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia.  Blood. 2010;  115 2755-2762