Transesterification of α-Amino Esters Catalyzed by a Tetranuclear Zinc Cluster: Zn₄(OCOCF₃)₆O

Abstract

Transesterification of amino acid ester derivatives was developed using a tetranuclear zinc cluster, Zn₄(OCOCF₃)₆O, as the catalyst. Because the reaction conditions were very mild, a variety of N-protective groups and functional groups on side chains were tolerated.

transesterification - esters - zinc - amino acids - clusters

References and Notes

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No peak corresponding to amide was found in the ^¹H NMR spectrum of the crude product before Cbz protection.