Neues aus der Arthroseforschung

Schlüsselwörter

Arthrose - Osteoarthrose - Knorpelmatrix

Keywords

osteoarthritis - cartilaginous matrix

• Literatur

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• 2 Blankenhorn EP et al. Genetic loci that regulate healing and regeneration in LG/J and SM/J mice. Mamm Genome 2009; 20: 720-733
• 3 Buckland-Wright JC, Lynch JA, Dave B. Early radiographic features in patients with anterior cruciate ligament rupture. Ann Rheum Dis 2000; 59: 641-646
• 4 Catterall JB et al. Protein modification by deamidation indicates variations in joint extracellular matrix turnover. J Biol Chem 2012; 287: 4640-4651
• 5 Chang HX, Yang L, Li Z et al. Age-related biological characterization of mesenchymal progenitor cells in human articular cartilage. Orthopedics 2011; 34: e382-388
• 6 Chapman K et al. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility. Hum Mol Genet 2008; 17: 1497-1504
• 7 Day JS et al. A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage. J Orthop Res 2001; 19: 914-918
• 8 Deberg M et al. New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage 2005; 13: 258-265
• 9 Echtermeyer F et al. Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis. Nat Med 2009; 15: 1072-1076
• 10 Endres M et al. Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells. Osteoarthritis Cartilage 2010; 18: 1458-1466
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• 13 Garvican ER, Vaughan-Thomas A, Innes JF et al. Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis. Vet J 2010; 185: 36-42
• 14 Henrotin Y et al. Fibulin-3 peptides (Fib3-1 and Fib3-2) are potential biomarkers of osteoarthritis. Arthritis Rheum 2012; 64: 2260-2267
• 15 Ikeuchi M, Takahashi T, Tani T. Localized synovial hypertrophy in the anteromedial compartment of the osteoarthritic knee. Arthroscopy 2005; 21: 1457-1461
• 16 Intema F et al. In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model. Osteoarthritis Cartilage 2010; 18: 691-698
• 17 Lotz M et al. Interleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes. Proc Nat Acad Sci 1995; 92: 10364-10368
• 18 Meulenbelt I et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet 2008; 17: 1867-1875
• 19 Saito T, Kawaguchi H. HIF-2alpha as a possible therapeutic target of osteoarthritis. Osteoarthritis Cartilage 2010; 18: 1552-1556
• 20 Saito T et al. Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat Med 2010; 16: 678-686
• 21 Wang Q et al. Identification of a central role for complement in osteoarthritis. Nat Med 2011; 17: 1674-1679