Download PDF
Neonatologie Scan 2013; 02(01): 49-60
DOI: 10.1055/s-0032-1326094
Fortbildung
© Georg Thieme Verlag KG Stuttgart · New York

Problemkeime auf der neonatologischen Intensivstation – mikrobiologischer Hintergrund und Hygienestrategien

Brigitte König
Further Information

Publication History

Publication Date:
04 March 2013 (online)

Also available at
    Permissions and Reprints

Einleitung

1967 schien es für William Stuart, den Surgeon General der Vereinigten Staaten von Amerika, klar zu sein, dass das Buch der Infektionskrankheiten geschlossen werden kann.

William Stuart, Surgeon General of the United States of America: „The time has come to close the book on infectious diseases. We have basically wiped out infection in the United States.”

Leider hat sich seine Prognose nicht bewahrheitet, weder in den USA noch anderswo.

 

  • Literatur

  • 1 Peterson LR. Bad bugs, no drugs: no ESCAPE revisited. Clin Infect Dis 2009; 49: 992-993
    CrossrefGoogle Scholar
  • 2 Safdar N, Maki DG. The commonality of risk factors for nosocomial colonization and infection with antimicrobial-resistant Staphylococcus aureus, enterococcus, gram-negative bacilli, Clostridium difficile, and Candida. Ann Intern Med 2002; 136: 834-844
    CrossrefGoogle Scholar
  • 3 Howard DH, Scott 2nd RD, Packard R et al. The global impact of drug resistance. Clin Infect Dis 2003; 36: 4-10
    CrossrefGoogle Scholar
  • 4 Paterson DL, Bonomo RA. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 2005; 18: 657-686
    CrossrefGoogle Scholar
  • 5 Faust K, Göpel W, Herting E et al. Sepsis bei Frühgeborenen mit einem sehr niedrigen Geburtsgewicht. Epidemiologie, Risikofaktoren und Präventionsstrategien. Chemotherapy Journal 2011; 20: 1
    Google Scholar
  • 6 Gonzalez-Vertiz A, Alcantar-Curiel D, Cuauhtli M et al. Multiresistant extended-spectrum beta-lactamase-producing Klebsiella pneumoniae causing an outbreak of nosocomial bloodstream infection. Infect Control Hosp Epidemiol 2001; 22: 723-725
    CrossrefGoogle Scholar
  • 7 Tschudin-Sutter S, Frei R, Battegay M et al. Extended spectrum ß-lactamase-producing Escherichia coli in neonatal care unit. Emerg Infect Dis 2010; 16: 1758-1760
    CrossrefGoogle Scholar
  • 8 Gupta A, Della-Latta P, Todd B et al. Outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit linked to artificial nails. Infect Control Hosp Epidemiol 2004; 25: 210-215
    CrossrefPubMedGoogle Scholar
  • 9 Chiu S, Huang YC, Lien RI et al. Clinical features of nosocomial infections by extended-spectrum beta-lactamase-producing Enterobacteriaceae in neonatal intensive care units. Acta Paediatr 2005; 94: 1644-1649
    CrossrefGoogle Scholar
  • 10 Velasco C, Rodríguez-Baño J, García L et al. Eradication of an extensive outbreak in a neonatal unit caused by two sequential Klebsiella pneumoniae clones harbouring related plasmids encoding an extended-spectrum beta-lactamase. J Hosp Infect 2009; 73: 157-163
    CrossrefGoogle Scholar
  • 11 Moissenet D et al. Meningitis caused by Escherichia coli producing TEM-52 extended-spectrum-lactamase within an extensive outbreak in a neonatal ward: epidemiological investigation and characterization of the strain. J Clin Microbiol 2010; 48: 2459-2463
    CrossrefGoogle Scholar
  • 12 Tschudin-Sutter S, Frei R, Battegay M et al. Extended-spectrum-lactamase-producing Escherichia coli in neonatal care unit. Emerg Infect Dis 2010; 16: 1758-1760
    CrossrefGoogle Scholar
  • 13 Oteo J, Cercenado E, Fernández-Romero S et al. Extended-Spectrum-Lactamase-Producing Escherichia coli as a Cause of Pediatric Infections: Report of a Neonatal Intensive Care Unit Outbreak Due to a CTX-M-14-Producing Strain. Antimicrobial Agents and Chemotherapy 2011; 54-58
    Google Scholar
  • 14 Hammerum AM, Lester CH, Jakobsen L et al. Faecal carriage of extended-spectrum β-lactamase-producing and AmpC β-lactamase-producing bacteria among Danish army recruits. Clin Microbiol Infect 2011; 17: 566-568
    CrossrefGoogle Scholar
  • 15 Vinué L, Sáenz Y, Martínez S et al. Prevalence and diversity of extended-spectrum beta-lactamases in faecal Escherichia coli isolates from healthy humans in Spain. Clin Microbiol Infect 2009; 15: 954-957
    CrossrefGoogle Scholar
  • 16 Rodríguez-Baño J, López-Cerero L, Navarro MD et al. Faecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli: prevalence, risk factors and molecular epidemiology. J Antimicrob Chemother 2008; 62: 1142-1149
    CrossrefGoogle Scholar
  • 17 Leverstein-van Hall MA, Dierikx CM, Cohen Stuart J et al. Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains. Clin Microbiol Infect 2011; 17: 873-880
    CrossrefGoogle Scholar
  • 18 Pfeifer Y, Cullik A, Witte W. Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int J Med Microbiol 2010; 300: 371-379
    CrossrefPubMedGoogle Scholar
  • 19 Robert Koch-Institut. Epidemiologisches Bulletin 2011; (26) 233
  • 20 Robert Koch-Institut. ARS. Im Internet: https://ars.rki.de Zugriff am 31.05.2012
    Google Scholar
  • 21 Cuny C, Layer F, Witte W. Staphylococcus aureus and MRSA in thawing liquid of broiler chicken carcasses and their relation to clonal lineages from humans. ZOV01 . DGHM; 2011
    Google Scholar
  • 22 Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for ß-lactamases and its correlation to molecular structure. Antimicrob Agents Chemother 1995; 39: 1211-1233
    CrossrefGoogle Scholar
  • 23 Ambler RP. The structure of beta-lactamases. Philos Trans R Soc Lond B Biol Sci 1980; 289: 321-331
    CrossrefGoogle Scholar
  • 24 Pfeifer Y. ESBL und AmpC: Laktamasen als eine Hauptursache der Cephalosporin-Resistenz bei Enterobakterien. Epidemiol Bulletin Nr. 28. RKI; 2007 Im Internet: http://memiserf.medmikro.ruhr-uni-bochum.de/nrz/anleitung_Hodge-Test_20120206 Zugriff am 30.11.2012
    Google Scholar
  • 25 Baum H, Kaase M, Meyer E et al. Robert Koch-Institut. Epidemiologisches Bulletin 2011; (36) 337-338