Pfortaderembolisation zur Konditionierung erweiterter Leberresektionen – aktueller Stand und Ausblick^[*]

Zusammenfassung

Erweiterte Leberresektionen gehen mit dem Risiko einer postoperativen Leberdysfunktion bis hin zum Leberversagen einher. Im Rahmen multimodaler Therapiekonzepte werden Patienten vor einer erweiterten Leberresektion deshalb konditioniert. Dieses Konzept beinhaltet die Durchführung einer sogenannten Pfortaderembolisation, die zum Ziel hat, das postoperativ in situ verbleibende Lebergewebe zum Wachstum anzuregen und somit das Risiko einer postoperativen Leberdysfunktion zu minimieren. Die vorliegende Arbeit fasst den aktuellen Stand dieser Intervention als Konditionierungsmaßnahme vor erweiterten Leberresektionen zusammen.

Abstract

Extended liver resections are associated with the risk of postoperative liver dysfunction up to liver failure. For this reason, prior to extended liver resections patients are conditioned in multi-modal therapy regimes. Portal vein embolisation is an essential part of such a multi-modal therapy. The aim of this intervention is an induction of hypertrophy of the future remnant liver volume. Thereby, the risk of postoperative liver failure is decreased. This article summarises the actual aspects of portal vein embolisation prior to extended liver resections.

Schlüsselwörter

Leberchirurgie - Leberresektion - Leberversagen - Pfortaderembolisation - zweizeitige Leberresektion

Key words

liver surgery - liver resection - liver failure - portal vein embolisation - two-stage liver resection

^* Prof. Dr. Dr. H. Lippert gewidmet

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