Synthesis of Cannabinol by a Modified Ullmann–Ziegler Cross-Coupling

Max P. Nüllen; Richard Göttlich

doi:10.1055/s-0033-1338428

Synlett, Table of Contents

Synlett 2013; 24(9): 1109-1112
DOI: 10.1055/s-0033-1338428

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Synthesis of Cannabinol by a Modified Ullmann–Ziegler Cross-Coupling

Max P. Nüllen

Institut für Organische Chemie, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 58, 35392 Gießen, Germany Fax: +49(641)9934349 Email: richard.goettlich@org.chemie.uni-giessen.de

,

Richard Göttlich*

Institut für Organische Chemie, Justus-Liebig-Universität Gießen, Heinrich-Buff-Ring 58, 35392 Gießen, Germany Fax: +49(641)9934349 Email: richard.goettlich@org.chemie.uni-giessen.de

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Abstract

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Abstract

Cannabinol, a pharmaceutically interesting component of cannabis, was prepared by a modified Ullmann–Ziegler cross-coupling. Using easily obtainable starting materials, this convergent approach allows facile access to a variety of cannabinol derivatives.

Key words

natural products - cross-coupling - palladium - copper - cannabinoids

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References

References and Notes
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