Tandem Hydroformylation–Biginelli Reaction

Abstract

The combination of a tandem process with a multicomponent reaction is a new approach to high atom-economic synthesis. A tandem hydroformylation–Biginelli reaction sequence has been developed leading to a variety of functionalized 4-alkyl-substituted 3,4-dihydropyrimidin-2(1H)-ones.

Key words

hydroformylation - Biginelli reaction - tandem reaction - multicomponent reaction - rhodium

• References and Notes

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