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Synlett 2014; 25(07): 975-976
DOI: 10.1055/s-0033-1340834
DOI: 10.1055/s-0033-1340834
letter
Stereoselective Total Synthesis of psiAβ – A Sporogenic Psi Factor from Aspergillus nidulans [1]
Further Information
Publication History
Received: 06 December 2013
Accepted after revision: 27 January 2014
Publication Date:
13 February 2014 (online)
Abstract
The stereoselective total synthesis of psiAβ, a sporogenic psi factor of the fungus Aspergillus nidulans, has been accomplished starting from pentane-1,5-diol. The synthesis involves an enantioselective Keck allylation, an asymmetric alkynylzinc addition, and a TEMPO–bis(acetoxy)iodobenzene (BAIB) oxidation as the key steps.
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References and Notes
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