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Synlett 2014; 25(09): 1246-1252
DOI: 10.1055/s-0033-1341201
DOI: 10.1055/s-0033-1341201
letter
Palladium-Catalyzed Interceptive Decarboxylative Addition of Allyl Carbonates with Carbonyl Group
Autoren
Weitere Informationen
Publikationsverlauf
Received: 10. Februar 2014
Accepted after revision: 19. März 2014
Publikationsdatum:
10. April 2014 (online)
Abstract
The first palladium-catalyzed interceptive decarboxylative 1,4-addition of allyl carbonates with squarates is reported. Interestingly, the C-3 carbonyl group of N-substituted isatins undergoes smooth decarboxylative 1,2-addition with allyl carbonates. This transformation offers a straightforward method for the synthesis of spiro-oxepane-fused 2-oxindole.
Key words
palladium - allylation - conjugate addition - allyl complexes - spiro compounds - metathesisSupporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information (PDF) (opens in new window)
-
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