Dialyse aktuell 2013; 17(6): 310-314
DOI: 10.1055/s-0033-1347112
Dialyse
© Georg Thieme Verlag Stuttgart · New York

Peritonealdialyse – Eine Behandlung für fast alle Dialysepatienten?

Peritoneal dialysis – A treatment for nearly every dialysis patient?
Marianne Haag-Weber
1   Sektion Nephrologie, Klinikum St. Elisabeth Straubing (Leitung: Prof. Dr. Marianne Haag-Weber)
› Author Affiliations
Further Information

Publication History

Publication Date:
22 July 2013 (online)

Trotz der Vorteile der Peritonealdialyse (PD) gerade zu Dialysebeginn ist die PD insbesondere in Deutschland unterrepräsentiert. Es gibt nur wenige Kontraindikationen für die PD. Es konnte gezeigt werden, dass die PD bei Zystennieren mit guten Ergebnissen durchgeführt werden kann. Aszites ist keine Kontraindikation, sondern eine medizinische Indikation für die PD. Auch bei Transplantatversagen und Immunsuppression kann die PD ohne größere Komplikationen durchgeführt werden. PEG-Anlagen sind keine Kontraindikation für die PD. Verschiedene Studien konnten zeigen, dass eine PD bei hohem Body-Mass-Index möglich ist. Die PD hat bei älteren Patienten viele Vorteile. Problematisch ist jedoch, dass viele ältere Patienten eine Assistenz benötigen. Assistenz durch Pflegepersonal ist in einigen Ländern etabliert. In Deutschland laufen einige Pilotprojekte. Bei ungeplantem Dialysestart wird in der Regel die Hämodialyse (HD) gewählt. Mit entsprechender Infrastruktur kann auch hier mit der PD begonnen werden.

Despite several advantages of peritoneal dialysis (PD) particularly at the start of dialysis, especially in Germany PD is still underutilized. There are only a few contraindications for PD. Good clinical results are observed with PD in patients with polycystic kidney disease. Ascites should not longer be considered as contraindication for PD, but as medical indication for PD. Failure of kidney transplantation and immunosuppression are no contraindication for PD. Peritoneal dialysis is possible for patients with high body mass index. Peritoneal dialysis has many advantages in elderly patients. The main barrier for PD in these patients is that many patients need some assistance. In some countries, assisted PD is well established. In Germany, there are several pilot projects. Hemodialysis is regularly chosen in the case of unplanned start of dialysis. With appropriate structures, unplanned dialysis could also be started with PD.

 
  • Literatur

  • 1 Fenton SS, Schaubel DE, Desmules M et al. Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis 1997; 30: 334-342
  • 2 Haef JG, Lokkegaard H, Madsen M. Initial survival advantage of peritoneal dialysis relative to hemodialysis. Nephrol Dial Int 2002; 17: 112-117
  • 3 Lukowsky RS, Mehrotra R, Kheifets L et al. Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy: a marginal structural model analysis. Clin J Am Soc Nephrol 2013; 8: 619-628
  • 4 Versorgungsleitlinien für Nierenerkrankung bei Diabetes im Erwachsenenalter. 11/2011
  • 5 Kumar S, Fan SLS, Raftery MJ, Yaqoob MM. Long term outcome of patients with autosomal dominant polycystic kidney diseases receiving peritoneal dialysis. Kidney Int 2008; 74: 946-951
  • 6 Lin L, Szeto CC, Kwan BC et al. Peritoneal dialysis as the first-line renal replacement therapy in patients with autosomal dominant polycystic kidney disease. Am J Kidney Dis 2011; 57: 903-907
  • 7 Lobbedez T, Touam M, Evans D et al. Peritoneal dialysis in polycystic kidney disease patients. Report from the French peritoneal dialysis registry (RDPLF). Nephrol Dial Int 2011; 26: 2332-2339
  • 8 Ruiz SR, Vilchez EG, Frias TPG et al. The role peritoneal dialysis in the treatment of ascites. Nefrologia 2011; 31: 648-655
  • 9 Zheng D, Chen LT, Han QF et al. Refractory ascites due to portal hypertension in autosomal dominant polycastic kidney disease (APKD) patients successfully treated with peritoneal dialysis. Perit Dial In 2010; 30: 151-155
  • 10 Selgas R, delPeso G, Bajo MA. Intra-abdominal hypertension favours ascites. Perit Dial Int 2010; 30: 156-157
  • 11 Padillo-Ruiz J, Arjona-Sanchez A, Munaz-Casares C et al. Impact of peritoneal dialysis versus hemodialysis on incidence of intra-abdominal infection after simultaneous pancreas-kidney transplantation. Worl J Surg 2010; 34: 1684-1688
  • 12 Perl J, Hasan O, Bargman JM et al. Impact of dialysis modality on survival after kidney transplant failure. Clin J Am Soc Nephrol 2011; 6: 582-590
  • 13 De Jonghe H, Bammens B, Lemahieu W et al. Comparison of peritoneal dialysis and hemodialysis after renal transplantation. Nephrol Dial Transplant 2006; 21: 1669-1674
  • 14 Perl J, Jassal SV, Bargman JM. Persistent peritoneal dialysis exit-site leak in a patient receiving maintenance immunosuppression with sirolimus. Clin Transplant 2008; 22: 672-673
  • 15 Corneli T, Rioux JP, Bargman JM, Chan CR. Home dialysis is a successful strategy in nonrenal solid organ transplant recipients with end-stage renaldisease. Nephrol Dial Transplant 2010; 25: 3425-3429
  • 16 Fein PA, Madane SJ, Jorden A et al. Outcome of percutaneous endoscopic gastrostomy feeding in patients on peritoneal dialysis. Adv Perit Dial 2001; 17: 148-152
  • 17 Penner T, Crabtree JH. Peritoneal dialysis catheter with back exit sites. Perit Dial Int 2013; 33: 83-88
  • 18 Lievense H, Kalantar-Zadeh K, Lukowsky LR et al. Relationship of body size and initial dialysis modality on subsequent transplantation, mortality and weight gain of ESRD patients. Nephrol Dial Transplant 2012; 27: 3631-3638
  • 19 Fernandes NMS, Bastos MG, Franco MRG et al. Body size and longitudial body weight changes do not increase mortality in incident peritoneal dialysis patients of the Brazilian peritoneal dialysis multi-center study. Clinic 2013; 68: 51-58
  • 20 Nessim SJ, Komenda P, Rigatto C et al. Frequency and microbiology of peritonitis and exit-site infection among obese peritoneal dialysis patients. Perit Dial Int 2013; 33: 167-174
  • 21 Smyth A. End-stage renal disease and renal replacement therapy in older patients. Nephro-Urol Mon 2012; 4: 425-430
  • 22 Berger JR, Hedayati SS. Renal replacement therapy in the elderly population. Clin J Am Soc Nephrol 2012; 7: 1039-1046
  • 23 Lamping DL, Constantinovici N, Roderick P et al. Clinical outcomes, quality of life, and costs in the North Thames Dialysis Study of elderly people on dialysis: a prospective cohort study. Lancet 2000; 356: 1543-1550
  • 24 Couchoud C, Moranne O, Frimat L et al. Associations between cormorbidities, treatment choice and outcome in the elderly with end-stage renal disease. Nephrol Dial Transplant 2007; 22: 3246-3254
  • 25 Brown EA, Johansson L, Farrington K et al. Broadening options for long-term dialysis in the elderly (BOLDE): differences in quality of life on peritonela dialysis compared to hemodialysis for older patients. Nephrol Dial Transplant 2010; 25: 3755-3763
  • 26 Verger C, Ryckelynck JP, Duman M et al. French Peritoneal Dialysis Registry: outline and main results. Kidney Int Suppl 2006; 103
  • 27 Povlsen JV, Ivarsen P. How to start the late referred ESRD patient urgently on chronic APD. Nephrol Dial Transplant 2006; 21 (Suppl. 02) 56-59
  • 28 Koch M, Kohnle M, Trapp R et al. Comparable outcome of acute unplanned peritoneal dialysis and haemodialysis. Nephrol Dial Transplant 2012; 27: 375-380
  • 29 Dombros N, Dratwa M, Fereiani M et al. European best practice guideline for peritoneal dialysis. 3. Peritoneal dialysis access. Nephrol Dial Transplant 2005; 20 (Suppl. 09) 8-12
  • 30 Yang YF, Wang HJ, Yeh CC et al. Early initiation of continuous ambulatory peritoneal dialysis in patients undergoing surgical implantation of Tenckhoff catheters. Peri Dial Int 2011; 31: 551-557