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Thorac Cardiovasc Surg 2014; 62(04): 324-331
DOI: 10.1055/s-0033-1351194
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Cardiac Liposarcoma—A Review of Outcome after Surgical Resection

Antje-Christin Deppe
1   Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany
*   These authors contributed equally to this work.
,
Christoph Adler
2   Department of Internal Medicine III, University of Cologne, Cologne, Germany
*   These authors contributed equally to this work.
,
Navid Madershahian
1   Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany
,
Hannes Reuter
2   Department of Internal Medicine III, University of Cologne, Cologne, Germany
,
Christopher Bangard
3   Institute and Policlinic of Radiological Diagnostics, University of Cologne, Cologne, Germany
,
Stephan Baldus
2   Department of Internal Medicine III, University of Cologne, Cologne, Germany
,
Thorsten Wahlers
1   Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany
,
Jens Wippermann
1   Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany
› Author Affiliations
Further Information

Publication History

19 April 2013

19 June 2013

Publication Date:
23 July 2013 (online)

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Abstract

Objective This review was performed to pool the current surgical strategies for cardiac liposarcoma.

Methods A literature search was performed and all studies published in full-text or abstract forms were eligible for inclusion without applying any language restrictions. Case reports without surgical intervention, reporting noncardiac liposarcoma, animal cases, or review articles were excluded after initial abstract review. Analyzed postoperative outcomes included intraoperative and in-hospital mortality, longest reported survival, and recrudescence.

Results After a critical evaluation 53 unique surgically treated case reports published between the years 1966 and December 2012 were included in this review. Most of the reported cardiac liposarcoma are myxoid (49.1%), pleomorphic liposarcoma occur with a prevalence of 20.8%, and well-differentiated tumors are observed in 13.2%. One-year survival rate increases the more differentiated the tumor is categorized: 54.5% for pleomorphic, 65.4% for myxoid, and 100% for well-differentiated liposarcoma (p = 0.096).

Conclusion Total surgical resection of cardiac liposarcoma is the only curative option, as it tends to local and distant recurrence. Therefore, a frequent follow-up examination should be considered.

Keywords

cardiac liposarcoma - cardiac - surgery