Oocyte Development and Loss

Roger G. Gosden

doi:10.1055/s-0033-1356475

Seminars in Reproductive Medicine, Table of Contents

Semin Reprod Med 2013; 31(06): 393-398
DOI: 10.1055/s-0033-1356475

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Oocyte Development and Loss

Roger G. Gosden

¹Center for Reproductive Medicine and Infertility, Weill Cornell Medical College, New York, New York

› Author Affiliations

Abstract

Soon after implantation, cell lineages bifurcate into future somatic and germ cells. Canonical expression of germ cell–specific genes continues during and after their migration to the gonadal ridge, where, after further cell cycles, they enter meiosis, form syncytial clusters, and arrest at diplotene for folliculogenesis. The balance between cell survival and death leaves an ovarian follicular reserve as a legacy.

Keywords

age - follicle - germ cell - oocyte - ovarian reserve

Full Text

References

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