Sportverletz Sportschaden 2015; 29(01): 27-39
DOI: 10.1055/s-0034-1385731
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Fußballsport als Risikofaktor für nicht unfallbedingte Gonarthrose – Ergebnisse eines systematischen Review mit Metaanalyse

Football as Risk Factor for a Non-Injury-Related Knee Osteoarthritis – Results from a Systematic Review and Metaanalysis
G. Spahn
1   Praxisklinik für Unfallchirurgie und Orthopädie Eisenach
,
V. Grosser
2   Berufsgenossenschaftliches Unfallkrankenhaus Hamburg
,
M. Schiltenwolf
3   Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Heidelberg
,
F. Schröter
4   Interdisziplinäre Med. Begutachtung, Kassel
,
J. Grifka
5   Asklepios Klinikum Bad Abbach GmbH, Bad Abbach
› Author Affiliations
Further Information

Publication History

Publication Date:
23 March 2015 (online)

Zusammenfassung

Zielstellung und Hypothese: Anliegen dieses systematischen Review mit anschließender Metaanalyse war es, den Einfluss des aktiven Fußballsports auf das Kniearthroserisiko (Relevanz als Berufserkrankung) zu untersuchen. Als Hypothese wurde formuliert: Fußballer leiden auch dann unter einem erhöhten Risiko für eine Gonarthrose, wenn sie keine dokumentierten Makroverletzungen des Kniegelenks erlitten haben.

Methode: Für das systematische Literaturreview und die anschließende Metaanalyse wurden die PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Checklisten eingehalten. Zum Stichtag 1.2.2014 wurde eine systematische Recherche in den Datenbanken PubMed, Medline, Cochrane, EMBASE und Web-of-Science durchgeführt. Insgesamt 4649 Publikationen einem „Title-Abstract-Review“ unterworfen und schließlich 6 Publikationen in die Metaanalyse eingeschlossen.

Ergebnisse: Eine Längsschnittuntersuchung an einer Gesamtbevölkerung, die den Einfluss des Fußballsports auf das Gonarthroserisiko untersuchte, wurde nicht gefunden. Ein systematisches Cochrane-Review existierte ebenso nicht. In den Studien, in denen nur diejenigen Fälle berücksichtigt wurden, bei denen keine Makroverletzung stattgefunden hatte, bestand im Vergleich zu den jeweiligen Kontrollgruppen ein signifikant erhöhtes Risiko, eine Gonarthrose zu erleiden: 1,3 (95 % CI 1,0 – 1,7); I2 = 37,4 %; p = 0,002. Ohne Adjustierung auf dokumentierte Makroverletzungen oder einen Meniskusschaden haben Fußballer ein signifikant erhöhtes Gonarthroserisiko: (Relatives Risiko = 2,9 [95 % CI 2,0 – 4,1]; I2 = 56,3 %; p < 0,001).

Schlussfolgerungen: Im Hinblick auf die große Heterogenität der Belastung des Fußballerknies, aufgrund des Fehlens der Kenntnis über ein belastungskonformes Schadensbild und im Hinblick auf das Fehlen einer „Verdopplung des relativen Risiko in der exponierten Gruppe“ wird derzeit keine „BK-Reife“ und auch kein Tatbestand „wie-BK“ bezüglich der Gonarthrose beim Profifußballer gesehen.

Abstract

Aim and Hyopthesis: This systematic review and the metanalysis were performed to investigate the relation between football activity and the potential risk of knee osteoarthritis (possible occupational disease). It was hypothesised that soccer players suffer more than controls from knee osteoarthritis also in cases with an absence of documented major injuries.

Methods: The review and the metaanalysis were performed accordingly to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. On 2014.02.01 a search was conducted within the medical databases PubMed, Medline, Cochrane, EMBASE und Web-of-Science. A total of 4,649 papers underwent a "Title-Abstract-Review". Finally 6 publications were included in the metaanaylsis.

Results: There were no longitudinal community-based studies as well as no Cochrane Reviews regarding the risk of knee osteoarthritis in soccer players. After adjustment of major injuries of the knee, soccer players have a slightly increased risk for knee osteoarthritis: relative risk 1.3 (95 % CI 1.0 – 1.7); I2 = 37.4 %; p = 0.002. In contrast, in studies without differentiation of injured and non-injured knees, the relative risk was significantly increased: 2.9 (95 % CI 2.0 – 4.1); I2 = 56.3 %; p < 0.001.

Conclusions: Soccer players are a very heterogeneous group. The soccer player’s knee undergoes different loadings including minor and major injuries. But the individual load also strongly depends on the player's status, his position within the football field and many other factors. In the absence of a major trauma the soccer player has only a slightly increased risk for the development of osteoarthritis. Thus we conclude that an injury in professional football does not fulfil the characteristics of an occupational disease.

 
  • Literatur

  • 1 Andrzejewski M, Chmura J, Pluta B et al. Analysis of motor activities of professional soccer players. J Strength Cond Res 2012; 26: 1481-1488
  • 2 Aroen A, Loken S, Heir S et al. Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med 2004; 32: 211-215
  • 3 Ayral X, Gueguen A, Ike RW et al. Inter-observer reliability of the arthroscopic quantification of chondropathy of the knee. Osteoarthritis Cartilage 1998; 6: 160-166
  • 4 Bauer M, Jackson RW. Chondral lesions of the femoral condyles: a system of arthroscopic classification. Arthroscopy 1988; 4: 97-102
  • 5 Becker A, Gaulrapp H, Hess H. Injuries in women soccer – results of a prospective study – in cooperation with the German Football Association (DFB). Sportverletz Sportschaden 2006; 20: 196-200
  • 6 Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bone Joint Surg Am 2003; 85-A (Suppl. 02) 58-69
  • 7 Brophy RH, Lyman S, Chehab EL et al. Predictive value of prior injury on career in professional American football is affected by player position. Am J Sports Med 2009; 37: 768-775
  • 8 Brunner MC, Flower SP, Evancho AM et al. MRI of the athletic knee. Findings in asymptomatic professional basketball and collegiate football players. Invest Radiol 1989; 24: 72-75
  • 9 Bundesministerium für Arbeit und Soziales. Wissenschaftliche Begründung zur Berufskrankheit Nummer 2112 „Gonarthrose durch eine Tätigkeit im Knien oder vergleichbarer Kniebelastung mit einer kumulativen Einwirkungsdauer während des Arbeitslebens von mindestens 13 000 Stunden und einer Mindesteinwirkungsdauer von insgesamt einer Stunde pro Schicht“. BArbBl 2005; 10: 46-72
  • 10 Crema MD, Cibere J, Sayre EC et al. The relationship between subchondral sclerosis detected with MRI and cartilage loss in a cohort of subjects with knee pain: the knee osteoarthritis progression (KOAP) study. Osteoarthritis Cartilage 2014; 22: 540-546
  • 11 Dahaghin S, Tehrani-Banihashemi SA, Faezi ST et al. Squatting, sitting on the floor, or cycling: are life-long daily activities risk factors for clinical knee osteoarthritis? Stage III results of a community-based study. Arthritis Rheum 2009; 61: 1337-1342
  • 12 Deacon A, Bennell K, Kiss ZS et al. Osteoarthritis of the knee in retired, elite Australian Rules footballers. Med J Aust 1997; 166: 187-190
  • 13 Di Salvo V, Baron R, Gonzalez-Haro C et al. Sprinting analysis of elite soccer players during European Champions League and UEFA Cup matches. J Sports Sci 2010; 28: 1489-1494
  • 14 Drawer S, Fuller CW. Propensity for osteoarthritis and lower limb joint pain in retired professional soccer players. Br J Sports Med 2001; 35: 402-408
  • 15 Drust B, Atkinson G, Reilly T. Future perspectives in the evaluation of the physiological demands of soccer. Sports Med 2007; 37: 783-805
  • 16 Dvorak J, Grimm K, Schmied C et al. Development and implementation of a standardized precompetition medical assessment of international elite football players--2006 FIFA World Cup Germany. Clin J Sport Med 2009; 19: 316-321
  • 17 Dvorak J, Junge A, Derman W et al. Injuries and illnesses of football players during the 2010 FIFA World Cup. Br J Sports Med 2011; 45: 626-630
  • 18 Edwards S, Steele JR, Cook JL et al. Lower limb movement symmetry cannot be assumed when investigating the stop-jump landing. Med Sci Sports Exerc 2012; 44: 1123-1130
  • 19 Elleuch MH, Guermazi M, Mezghanni M et al. Knee osteoarthritis in 50 former top-level soccer players: a comparative study. Ann Readapt Med Phys 2008; 51: 174-178
  • 20 Flanigan DC, Harris JD, Trinh TQ et al. Prevalence of chondral defects in athletes' knees: a systematic review. Med Sci Sports Exerc 2010; 42: 1795-1801
  • 21 Fousekis K, Tsepis E, Vagenas G. Lower limb strength in professional soccer players: profile, asymmetry, and training age. J Sports Sci Med 2010; 9: 364-373
  • 22 Gantz S, Schindel R, Schneider S et al. Laufsport. Führt Laufsport zu vorzeitigen degenerativen Veränderungen am Kniegelenk?. Trauma Berufskrankh 2012; 14 (Suppl. 04) 446-451
  • 23 Gelber AC, Hochberg MC, Mead LA et al. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med 2000; 133: 321-328
  • 24 Gobbi A, Karnatzikos G, Sankineani SR. One-step surgery with multipotent stem cells for the treatment of large full-thickness chondral defects of the knee. Am J Sports Med 2014; 42: 648-657
  • 25 Goncalves BV, Figueira BE, Macas V et al. Effect of player position on movement behaviour, physical and physiological performances during an 11-a-side football game. J Sports Sci 2014; 32: 191-199
  • 26 Hackenbroch MH. Arthrosen. Basiswissen zu Klinik, Dioagnostik und Therapie. Stuttgart: Thieme; 2002
  • 27 Henrotin Y, Pesesse L, Sanchez C. Subchondral bone and osteoarthritis: biological and cellular aspects. Osteoporos Int 2012; 23 (Suppl. 08) S847-S851
  • 28 Higgins JP, Thompson SG, Deeks JJ et al. Measuring inconsistency in meta-analyses. BMJ 2003; 327: 557-560
  • 29 Hjelle K, Solheim E, Strand T et al. Articular cartilage defects in 1000 knee arthroscopies. Arthroscopy 2002; 18: 730-734
  • 30 Hofmann GO, Marticke J, Grossstuck R et al. Detection and evaluation of initial cartilage pathology in man: A comparison between MRT, arthroscopy and near-infrared spectroscopy (NIR) in their relation to initial knee pain. Pathophysiology 2010; 17: 1-8
  • 31 Junge A, Dvorak J. Injuries in female football players in top-level international tournaments. Br J Sports Med 2007; 41 (Suppl. 01) i3-i7
  • 32 Junge A, Dvorak J. Injury risk of playing football in Futsal World Cups. Br J Sports Med 2010; 44: 1089-1092
  • 33 Junge A, Dvorak J. Injury surveillance in the World Football Tournaments 1998-2012. Br J Sports Med 2013; 47: 782-788
  • 34 Junge A, Dvorak J, Graf-Baumann T. Football injuries during the World Cup 2002. Am J Sports Med 2004; 32: 23S-27S
  • 35 Junge A, Dvorak J, Graf-Baumann T et al. Football injuries during FIFA tournaments and the Olympic Games, 1998-2001: development and implementation of an injury-reporting system. Am J Sports Med 2004; 32: 80S-89S
  • 36 Junge A, Engebretsen L, Mountjoy ML et al. Sports injuries during the Summer Olympic Games 2008. Am J Sports Med 2009; 37: 2165-2172
  • 37 Junge A, Grimm K, Feddermann N et al. Precompetition orthopedic assessment of international elite football players. Clin J Sport Med 2009; 19: 326-328
  • 38 Junge A, Langevoort G, Pipe A et al. Injuries in team sport tournaments during the 2004 Olympic Games. Am J Sports Med 2006; 34: 565-576
  • 39 Kaplan LD, Schurhoff MR, Selesnick H et al. Magnetic resonance imaging of the knee in asymptomatic professional basketball players. Arthroscopy 2005; 21: 557-561
  • 40 Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957; 16: 494-502
  • 41 Kettunen JA, Kujala UM, Kaprio J et al. Lower-limb function among former elite male athletes. Am J Sports Med 2001; 29: 2-8
  • 42 Kim JH, Lee KK, Kong SJ et al. Effect of Anticipation on Lower Extremity Biomechanics During Side- and Cross-Cutting Maneuvers in Young Soccer Players. Am J Sports Med 2014; 42: 1985-1992
  • 43 Klug SJ, Bender R, Blettner M et al. Common study designs in epidemiology. Dtsch Med Wochenschr 2007; 132 (Suppl. 01) e45-e47
  • 44 Klunder KB, Rud B, Hansen J. Osteoarthritis of the hip and knee joint in retired football players. Acta Orthop Scand 1980; 51: 925-927
  • 45 Klussmann A, Gebhardt H, Nubling M et al. Individual and occupational risk factors for knee osteoarthritis: results of a case-control study in Germany. Arthritis Res Ther 2010; 12: 1-15
  • 46 Krajnc Z, Vogrin M, Recnik G et al. Increased risk of knee injuries and osteoarthritis in the non-dominant leg of former professional football players. Wien Klin Wochenschr 2010; 122 (Suppl. 02) 40-43
  • 47 Kujala UM, Kettunen J, Paananen H et al. Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters. Arthritis Rheum 1995; 38: 539-546
  • 48 Lau EC, Cooper C, Lam D et al. Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities. Am J Epidemiol 2000; 152: 855-862
  • 49 Liebers F, Latza U, Bolm-Audorff U et al. Übergewicht in der Ätiologie der Gonarthrose. Trauma Berufskrankh 2012; 14 (Suppl. 04) 414-433
  • 50 Lyle MA, Valero-Cuevas FJ, Gregor RJ et al. Control of dynamic foot-ground interactions in male and female soccer athletes: females exhibit reduced dexterity and higher limb stiffness during landing. J Biomech 2014; 47: 512-517
  • 51 Major NM, Helms CA. MR imaging of the knee: findings in asymptomatic collegiate basketball players. Am J Roentgenol 2002; 179: 641-644
  • 52 Mitchell LC, Ford KR, Minning S et al. Medial foot loading on ankle and knee biomechanics. N Am J Sports Phys Ther 2008; 3: 133-140
  • 53 Moretz III JA , Harlan SD, Goodrich J et al. Long-term followup of knee injuries in high school football players. Am J Sports Med 1984; 12: 298-300
  • 54 Myer GD, Ford KR, Di Stasi SL et al. High knee abduction moments are common risk factors for patellofemoral pain (PFP) and anterior cruciate ligament (ACL) injury in girls: Is PFP itself a predictor for subsequent ACL injury?. Br J Sports Med 2014; [Epub ahead of print]
  • 55 Myer GD, Ford KR, Foss KD et al. A Predictive Model to Estimate Knee-Abduction Moment: Implications for Development of a Clinically Applicable Patellofemoral Pain Screening Tool in Female Athletes. J Athl Train 2014; [Epub ahead of print]
  • 56 Noyes FR, Bassett RW, Grood ES et al. Arthroscopy in acute traumatic hemarthrosis of the knee. Incidence of anterior cruciate tears and other injuries. J Bone Joint Surg Am 1980; 62: 687-695
  • 57 Ostenberg A, Roos H. Injury risk factors in female European football. A prospective study of 123 players during one season. Scand J Med Sci Sports 2000; 10: 279-285
  • 58 Parkin DM, Bray FI. Concepts and methodological approaches in epidemiology. Descriptive Studies. In: Ahrens W, Pigeot I. Handbook of epidemiology. Berlin, Heidelberg, New York: Springer; 2005: 157-230
  • 59 Pollard CD, Sigward SM, Powers CM. Limited hip and knee flexion during landing is associated with increased frontal plane knee motion and moments. Clin Biomech (Bristol, Avon) 2010; 25: 142-146
  • 60 Radin EL, Parker HG, Pugh JW et al. Response of joints to impact loading. 3. Relationship between trabecular microfractures and cartilage degeneration. J Biomech 1973; 6: 51-57
  • 61 Radin EL, Paul IL. Response of joints to impact loading. I. In vitro wear. Arthritis Rheum 1971; 14: 356-362
  • 62 Radin EL, Paul IL, Rose RM. Role of mechanical factors in pathogenesis of primary osteoarthritis. Lancet 1972; 1: 519-522
  • 63 Radin EL, Swann DA, Paul IL et al. Factors influencing articular cartilage wear in vitro. Arthritis Rheum 1982; 25: 974-980
  • 64 Roemer FW, Eckstein F, Hayashi D et al. The role of imaging in osteoarthritis. Best Pract Res Clin Rheumatol 2014; 28: 31-60
  • 65 Roos H, Lindberg H, Gardsell P et al. The prevalence of gonarthrosis and its relation to meniscectomy in former soccer players. Am J Sports Med 1994; 22: 219-222
  • 66 Rustenbach SJ. Metaanalyse. Eine anwendungsorientierte Einführung. Huber: Bern, Göttingen, Toronto, Seattle; 2003
  • 67 Sandmark H, Vingard E. Sports and risk for severe osteoarthrosis of the knee. Scand J Med Sci Sports 1999; 9: 279-284
  • 68 Schmitz RJ, Cone JC, Tritsch AJ et al. Changes in drop-jump landing biomechanics during prolonged intermittent exercise. Sports Health 2014; 6: 128-135
  • 69 Schönberger A, Valentin H, Mehrtens G. Arbeitsunfall und Berufskrankheit. Rechtliche und medizinische Grundlagen für Gutachter, Sozialverwaltung, Berater und Gerichte. Berlin: Erich Schmidt Verlag GmbH & Co; 2010
  • 70 Sharma L, Kapoor D. Epidemiology of Osteoarthritis. In: Moskowitz RW, Altman R, Hochberg MC, et al. Diagnosis, Medical/Surgical Management. 2007: 3-26
  • 71 Shelbourne KD, Jari S, Gray T. Outcome of untreated traumatic articular cartilage defects of the knee: a natural history study. J Bone Joint Surg Am 2003; 85-A (Suppl. 02) 8-16
  • 72 Sigward SM, Powers CM. Loading characteristics of females exhibiting excessive valgus moments during cutting. Clin Biomech (Bristol, Avon) 2007; 22: 827-833
  • 73 Spahn G, Eberth F, Gantz S et al. Trauma. Trauma Berufskrankh 2012; 14 (Suppl. 04) 434-436
  • 74 Spahn G, Schiele R, Hofmann GO et al. The relative risk of knee osteoarthritis after knee injuries – results of a metaanalysis. Phys Med Rehab Kuror 2011; 21: 269-279
  • 75 Spahn G, Felmet G, Hofmann GO. Traumatic and degenerative cartilage lesions: arthroscopic differentiation using near-infrared spectroscopy (NIRS). Arch Orthop Trauma Surg 2013; 133: 997-1002
  • 76 Spahn G, Kahl E, Klinger HM et al. Mechanical behavior of intact and low-grade degenerated cartilage. Biomed Tech (Berl) 2007; 52: 216-222
  • 77 Spahn G, Plettenberg H, Kahl E et al. Near-infrared (NIR) spectroscopy. A new method for arthroscopic evaluation of low grade degenerated cartilage lesions. Results of a pilot study. BMC Musculoskelet Disord 2007; 8: 47
  • 78 Spahn G, Wittig R. Biomechanical properties (compressive strength and compressive pressure at break) of hyaline cartilage under axial load. Zentralbl Chir 2003; 128: 78-82
  • 79 Thelin N, Holmberg S, Thelin A. Knee injuries account for the sports-related increased risk of knee osteoarthritis. Scand J Med Sci Sports 2006; 16: 329-333
  • 80 Turner AP, Barlow JH, Heathcote-Elliott C. Long term health impact of playing professional football in the United Kingdom. Br J Sports Med 2000; 34: 332-336
  • 81 Tveit M, Rosengren BE, Nilsson JA et al. Former male elite athletes have a higher prevalence of osteoarthritis and arthroplasty in the hip and knee than expected. Am J Sports Med 2012; 40: 527-533
  • 82 Wehbe GM, Hartwig TB, Duncan CS. Movement analysis of Australian national league soccer players using global positioning system technology. J Strength Cond Res 2014; 28: 834-842
  • 83 Zagrodnik FD, Bolm-Audorff U, Eberth F et al. Außerberufliche Faktoren der Gonarthrose. Trauma Berufskrankh 2012; 14 (Suppl. 04) 399-401
  • 84 Zhang LZ, Zheng HA, Jiang Y et al. Mechanical and biologic link between cartilage and subchondral bone in osteoarthritis. Arthritis Care Res (Hoboken) 2012; 64: 960-967
  • 85 Ziegler A, Konig IR. Guidelines for research reports: German translation of CONSORT 2010, PRISMA and STARD. Dtsch Med Wochenschr 2011; 136: 357-358