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Thorac Cardiovasc Surg 2015; 63(07): 614-617
DOI: 10.1055/s-0034-1394161
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Sarcomatous Components May Predict Prognosis in Patients with Pulmonary Pleomorphic Carcinoma

Tetsuzo Tagawa
1   Department of General Thoracic Surgery, Chiba University, Chiba, Japan
,
Junichi Morimoto
1   Department of General Thoracic Surgery, Chiba University, Chiba, Japan
,
Shigetoshi Yoshida
1   Department of General Thoracic Surgery, Chiba University, Chiba, Japan
,
Ichiro Yoshino
1   Department of General Thoracic Surgery, Chiba University, Chiba, Japan
› Author Affiliations
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Publication History

08 June 2014

25 August 2014

Publication Date:
25 November 2014 (online)

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Abstract

Objectives and Methods Pulmonary pleomorphic carcinoma often presents with clinically aggressive behavior. We retrospectively reviewed 16 patients who underwent surgery from 1999 to 2013.

Results Sarcomatous components included spindle cell type in six (38%) patients, giant cell type in three (19%) patients, and mixed cell type in seven (44%) patients. The 5-year overall survival rate was 40.6%. On univariate analysis, spindle cell type, pN0, and small tumor diameter were associated with better prognosis. The 5-year survival of six patients with spindle cell type was 83.3%.

Conclusions Despite the small sample size, we suggest that patients with spindle cell type may have favorable prognoses.

Keywords

lung cancer - surgery - sarcoma
 

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