Verwendung von equinem Knochenersatzmaterial in der Zahnmedizin

Autologes Knochenersatzmaterial stellt noch immer den Goldstandard dar für Knochenregeneration in der Zahnmedizin [1]. Trotz geringer Komplikationen bei ihrer Einheilung, zeigen autologe Knochentransplantate eine Tendenz zur Resorption und bringen ein höheres Entnahmerisiko mit sich, wie Hypästhesien, Parästhesien und Funktionsstörungen [2] [3]. Eine sinnvolle Alternative zur Vermeidung der genannten Nachteile stellt die Anwendung allogener und xenogener Knochenersatzmaterialien dar [4].

• Literatur

• 1 Nienhuijs ME, Walboomers XF, Merkx MA et al. Bone-like tissue formation using an equine COLLOSS E-filled titanium scaffolding material. Biomaterials 2006; 27: 3109-3114
• 2 Perrotti V, Nicholls BM, Piattelli A. Human osteoclast formation and activity on an equine spongy bone substitute. Clin Oral Implants Res. 2009; 20: 17-23
• 3 Wang M. Developing bioactive composite materials for tissue replacement. Biomaterials 2003; 24: 2133-2151
• 4 Scarano A, Degidi M, Iezzi G et al. Maxillary sinus augmentation with different biomaterials: a comparative histologic and histomorphometric study in man. Implant Dent. 2006; 15: 197-207
• 5 Yildirim M, Spiekermann H et al. Maxillary sinus augmentation using xenogenic bone substitute material Bio-Oss in combination with venous blood. A histologic and histomorphometric study in humans. Clin Oral Implants Res 2000; 11: 217-229
• 6 Traini T, Valentini P et al. A histologic and histomorphometric evaluation of anorganic bovine bone retrieved 9 years after a sinus augmentation procedure. J Periodontol. 2007; 78: 955-961
• 7 Orsini G, Scarano A, Piattelli M et al. Histologic and ultrastructural analysis of regenerated bone in maxillary sinus augmentation using a porcine bone-derived biomaterial. J Periodontol. 2006; 77: 1984-1990
• 8 Barone A, Crespi R, Aldini NN et al. Maxillary sinus augmentation: histologic and histomorphometric analysis. Int J Oral Maxillofac Implants 2005; 20: 519-525
• 9 Scabbia A, Trombelli L. A comparative study on the use of a HA / collagen / chondroitin sulphate biomaterial (Biostite) and a bovine-derived HA xenograft (Bio-Oss) in the treatment of deep intra-osseous defects. J Clin Periodontol. 2004; 31: 348-355
• 10 Huffer WE, Benedict JJ et al. Osteoinduction with COLLOSS, COLLOSS E, and GFm. Adv Exp Med Biol. 2006; 585: 87-100
• 11 Li H, Springer M, Zou X et al. Ectopic bone induction by equine bone protein extract. Adv Exp Med Biol 2006; 585: 393-402
• 12 Perrotti V, Nicholls BM, Piattelli A. Human osteoclast formation and activity on an equine spongy bone substitute. Clin Oral Implants Res. 2009; 20: 17-23
• 13 Di Stefano DA, Artese L, Iezzi G et al. Alveolar ridge regeneration with equine spongy bone: a clinical,histological, and immunohistochemical case series. Clin Implant Dent Relat Res. 2009; 11: 90-100
• 14 Stievano D, Di Stefano A, Ludovichetti M et al. Maxillary sinus lift through heterologous bone grafts and simultaneous acid-etched implants placement. Five year follow-up. Minerva Chir. 2008; 63: 79-91