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ZWR - Das Deutsche Zahnärzteblatt 2015; 124(01): 18-24
DOI: 10.1055/s-0034-1398571
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Georg Thieme Verlag KG Stuttgart · New York

Kariesätiopathogenese aus mikrobiologischer Sicht – Aktueller Stand

S. Kneist
1   Erfurt/Mainz
,
A. Callaway
1   Erfurt/Mainz
› Author Affiliations
Further Information

Publication History

Publication Date:
18 February 2015 (online)

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Lernziele

Nach dem Durcharbeiten des Artikels sollte der Leser das zeitgemäße Wissen zur Kariesätiopathogenese aus mikrobiologischer Sicht erfasst haben:

  • den Terminus Plaque,

  • die Plaquehypothesen und die heute akzeptierte „Erweiterte ökologische Plaquehypothese“ reflektiert haben,

  • pH-Werte, die zur Demineralisation der Zahnhartgewebe führen, und die Rolle der Mütter für die Transmission oraler Keime einschätzen können.

 

  • Literatur

  • 1 Marsh PD. Microbial ecology of dental plaque and its significance in health and disease. Adv Dent Res 1994; 8: 263-271
    CrossrefPubMedGoogle Scholar
  • 2 Marsh PD. Dental plaque as a microbial biofilm. Caries Res 2004; 39: 204-211
    PubMedGoogle Scholar
  • 3 Beighton D. Can the ecology of the dental biofilm be beneficially altered?. Adv Dent Res 2009; 21: 69-73
    PubMedGoogle Scholar
  • 4 Takahashi N, Nyvad B. The role of bacteria in the caries process: Ecological perspectives. J Dent Res 2011; 90: 294-303
    CrossrefPubMedGoogle Scholar
  • 5 Keyes PH. Recent advances in dental caries research. Bacteriology, bacteriological findings, and biological implications. Int Dent J 1962; 12: 443-464
    PubMedGoogle Scholar
  • 6 König KG. Karies und Kariesprophylaxe. München: Goldmann; 1971
    Google Scholar
  • 7 Loesche WJ. Role of Streptococcus mutans in human dental decay. Microbiol Rev 1986; 50: 353-380
    PubMedGoogle Scholar
  • 8 van Houte J. Role of microorganisms in caries etiology. J Dent Res 1994; 73: 672-681
    PubMedGoogle Scholar
  • 9 van Houte J, Sansone C, Joshipura K et al. In vitro acidogenic potential and mutans streptococci of human smooth surface plaque associated with initial caries lesions and sound enamel. J Dent Res 1991; 70: 1497-1502
    CrossrefPubMedGoogle Scholar
  • 10 Houte J, van Sansone C, Joshipura K et al. Mutans streptococci and non-mutans streptococci acidogenic at low pH, and in vitro acidogenic potential of dental plaque in two different areas of the human dentition. J Dent Res 1991; 70: 1503-1507
    CrossrefPubMedGoogle Scholar
  • 11 Kleinberg I. A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. Crit Rev Oral Biol Med 2002; 13: 108-205
    CrossrefPubMedGoogle Scholar
  • 12 Soet JJde, Nyvad B, Kilian M. Strain-related acid production by oral streptococci. Caries Res 2000; 34: 486-490
    CrossrefPubMedGoogle Scholar
  • 13 Sansone C, van Houte J, Joshipura K et al. The association of mutans streptococci and non-mutans streptococci capable of acidogenesis at a low pH with dental caries on enamel and root surfaces. J Dent Res 1993; 72: 508-516
    CrossrefPubMedGoogle Scholar
  • 14 Alam S, Brailsford SR, Adams S et al. Genotypic heterogeneity of Streptococcus oralis and distinct aciduric subpopulations in human dental plaque. Appl Environ Microbiol 2000; 66: 3330-3336
    CrossrefPubMedGoogle Scholar
  • 15 Beighton D. Microflora of early childhood caries in relation to socio-demographic variables. Oralprophylaxe u. Kinderzahnheilkd 2010; 32: 89-92
    PubMedGoogle Scholar
  • 16 Baker-Dirks O. Posteruptive changes in dental enamel. J Dent Res 1966; 45: 502
    PubMedGoogle Scholar
  • 17 German B. Kariesbefall und Zahnverlust in der Altersspanne von 14 bis 23 Jahre. Eine Longitudinalstudie an 59 Probanden. Med Diss Zürich 1977;
    PubMedGoogle Scholar
  • 18 Stösser L, Kneist S, Heinrich-Weltzien R et al. Current Research on Caries Risk Assessment. In: Stookey GK. Hrsg Early Detection of Dental Caries II: Proceedings of the 4th Annual Indiana Conference Indianapolis, Indianapolis, IN: Indiana University School of Dentistry. 2000: 31-56
    Google Scholar
  • 19 Kneist S, Kubieziel H, Willershausen B et al. Modeling of S. mutans and A. naeslundii acid production in vitro with caries incidence of low- and high-risk children. Quintessence International 2012; 43: 413-420
    PubMedGoogle Scholar
  • 20 Kneist S, Borutta A. Zum Ursachenkomplex der frühkindlichen Karies und ihrer Vermeidung. ZWR 2005; 114: 286-292
    Article in Thieme ConnectPubMedGoogle Scholar
  • 21 Kneist S, Kozlik B Wagner A. Gesunderhaltung des Milchgebisses. Thüringenweites Engagement der Zahnärzte. TZB 2009; 2: I-IV
    PubMedGoogle Scholar
  • 22 Kneist S, Maslak E, Care R et al. Biologische und soziale Determinanten im Bedingungsgefüge der frühkindlichen Karies. Quintessenz 2010; 61: 435-442
    PubMedGoogle Scholar
  • 23 Kneist S, Heinrich-Weltzien R, Tietze W et al. The microbial colonization of the oral cavity as fundamental prerequisite for the caries risk – an overview of the findings from the Erfurt study. In: Stößer L. (eHrsg.) Caries dynamics and caries risk. Berlin: Quintessenz; 1998: 201-213
    Google Scholar
  • 24 Kneist S, Heinrich-Weltzien R, Rupf S et al. Zur Bedeutung von S. sobrinus für die Kariesentwicklung bei Kindern. Oralprophylaxe u. Kinderzahnheilkunde 2004; 26: 24-28
    PubMedGoogle Scholar
  • 25 Kneist S, Raser G, Nietzsche S et al. Modeling of Invasion into Hard Tissue – Generalists (S. sanguinis) versus Specialists (S. sobrinus). Caries Res 2013; 47, Abstracts: 60th ORCA Congress DOI: 10.1159/0003506702013.
    PubMedGoogle Scholar
  • 26 Weerheijm KL, de Soet JJ, de Graaf J et al. Occlusal hidden caries: a bacteriological profile. ASDC J Dent Child 1990; 57: 428-432
    PubMedGoogle Scholar
  • 27 Hammes W, Hertel C. Genus Lactobacillus. In de Vos P, Garrizy G, Jones D, Krieg NR, Ludwig W, Rainey FA, Schleifer K-H, Whitmann WP. Bergey’s Manual of Systematic Bacteriology. 2nd ed. Vol. 3. The Firmicutes Heidelberg: Springer; 2009: 465-510
    Google Scholar
  • 28 Badet C, Thebaud NB. Ecology of Lactobacilli in the oral cavity: A review of literature. Open Microbiol J 2008; 2: 38-48
    CrossrefPubMedGoogle Scholar
  • 29 Callaway A, Kostrzewa M, Willershausen B et al. Identification of lactobacilli from deep carious lesions by means of species-specific PCR and MALDI-TOF mass spectrometry. Clin Lab 2013; 59: 1373-1379
    PubMedGoogle Scholar
  • 30 Nyvad B, Crielaard W, Mira A et al. Dental Caries from a molecular microbiological perspective. Caries Res 2013; 47: 89-102
    CrossrefPubMedGoogle Scholar