Copper-Catalyzed Regioselective Sulfenylation of Thiazolo[3,2-b]-1,2,4-triazoles with Thiols

Abstract

A simple and useful protocol was developed for the regioselective copper-catalyzed direct sulfenylation of thiazolo[3,2-b]-1,2,4-triazoles with thiols. The reaction shows broad functional-group tolerance and provides rapid access to sulfenylated thiazolo[3,2-b]-1,2,4-triazoles in moderate to good yields.

Key words

sulfenylation - thiazolotriazoles - thiols - copper catalysis - regioselectivity

• References

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