Thorac Cardiovasc Surg 2017; 65(04): 265-271
DOI: 10.1055/s-0036-1584688
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Exclusive Bilateral Internal Thoracic Artery Grafts for Myocardial Revascularization Requiring Four Anastomoses or More: Outcomes from a Single Center Experience

Andrea Perrotti
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
,
Amedeo Spina
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
,
Enrica Dorigo
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
,
Camille Durst
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
,
Djamel Kaili
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
,
Sidney Chocron
1   Department of Cardiothoracic Surgery, Centre Hospitalier Universitaire de Besancon Ringgold Standard Institution, Besancon, France
› Author Affiliations
Further Information

Publication History

15 March 2016

19 May 2016

Publication Date:
01 July 2016 (online)

Abstract

Introduction Multivessel coronary artery bypass graft (CABG) with bilateral internal thoracic arteries (BITA) has only been uncommon and technically demanding. We describe our experience with BITA only CABGs requiring ≥ 4 anastomoses.

Material and Methods The department's database was queried for patients undergoing isolated CABG with ≥ 4 anastomoses. The surgical technique included systematically a right internal thoracic artery (ITA) of left ITA Y graft. The multivariate model included variables with a p < 0.3 at univariate analysis.

Results Between January 2006 and December 2009, 251 consecutive patients (71 ± 10 years) (on-pump: 130, off-pump: 121) had CABG with ≥ 4 anastomoses, representing 21% of total isolated CABGs for the same period; all patients received a totally arterial BITA only revascularization. Follow-up was 4.9 ± 1.6 years. Overall and cardiac cumulative survivals were 78 and 92%, respectively, at 5 years. The occurrence of any major postoperative complication was associated with overall and cardiac mortality (odds ratio [OR]: 3.6, 95% confidence interval [CI]: 1.3–9.9 and OR: 5.4, 95% CI: 1.3–21.9, respectively). Major sternal wound complication requiring surgical revision was not associated with impaired glucose control (n = 9; diabetics: 6/82, 7.3%; nondiabetics: 3/169, 1.8%, p = 0.06). Preoperative kidney failure was associated with incomplete revascularization (OR: 6.2; 95% CI: 1.2–33.5), that was unfailingly due to ungraftable right coronary artery targets.

Discussion BITA only revascularization was a valuable and safe procedure, with favorable results in terms of morbidity and mortality at a 5 years' follow-up.

 
  • References

  • 1 Takagi H, Goto SN, Watanabe T, Mizuno Y, Kawai N, Umemoto T. A meta-analysis of adjusted hazard ratios from 20 observational studies of bilateral versus single internal thoracic artery coronary artery bypass grafting. J Thorac Cardiovasc Surg 2014; 148 (4) 1282-1290
  • 2 Tabata M, Grab JD, Khalpey Z , et al. Prevalence and variability of internal mammary artery graft use in contemporary multivessel coronary artery bypass graft surgery: analysis of the Society of Thoracic Surgeons National Cardiac Database. Circulation 2009; 120 (11) 935-940
  • 3 Dalén M, Ivert T, Holzmann MJ, Sartipy U. Bilateral versus single internal mammary coronary artery bypass grafting in Sweden from 1997-2008. PLoS ONE 2014; 9 (1) e86929
  • 4 He GW, Ryan WH, Acuff TE , et al. Risk factors for operative mortality and sternal wound infection in bilateral internal mammary artery grafting. J Thorac Cardiovasc Surg 1994; 107 (1) 196-202
  • 5 Yi G, Shine B, Rehman SM, Altman DG, Taggart DP. Effect of bilateral internal mammary artery grafts on long-term survival: a meta-analysis approach. Circulation 2014; 130 (7) 539-545
  • 6 Tatoulis J, Buxton BF, Fuller JA. The right internal thoracic artery: the forgotten conduit—5,766 patients and 991 angiograms. Ann Thorac Surg 2011; 92 (1) 9-15 , discussion 15–17
  • 7 Baskett RJ, Cafferty FH, Powell SJ, Kinsman R, Keogh BE, Nashef SA. Total arterial revascularization is safe: multicenter ten-year analysis of 71,470 coronary procedures. Ann Thorac Surg 2006; 81 (4) 1243-1248
  • 8 Zingone B. Stenting the coronaries and bypassing the evidence in patients with multivessel coronary artery disease: time to set the record straight. J Cardiovasc Med (Hagerstown) 2007; 8 (5) 362-370
  • 9 Shahian DM, O'Brien SM, Sheng S , et al. Predictors of long-term survival after coronary artery bypass grafting surgery: results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database (the ASCERT study). Circulation 2012; 125 (12) 1491-1500
  • 10 Lytle BW, Blackstone EH, Loop FD , et al. Two internal thoracic artery grafts are better than one. J Thorac Cardiovasc Surg 1999; 117 (5) 855-872
  • 11 Deo SV, Shah IK, Dunlay SM , et al. Bilateral internal thoracic artery harvest and deep sternal wound infection in diabetic patients. Ann Thorac Surg 2013; 95 (3) 862-869
  • 12 Dorman MJ, Kurlansky PA, Traad EA, Galbut DL, Zucker M, Ebra G. Bilateral internal mammary artery grafting enhances survival in diabetic patients: a 30-year follow-up of propensity score-matched cohorts. Circulation 2012; 126 (25) 2935-2942
  • 13 Mohammadi S, Dagenais F, Doyle D , et al. Age cut-off for the loss of benefit from bilateral internal thoracic artery grafting. Eur J Cardiothorac Surg 2008; 33 (6) 977-982
  • 14 Muneretto C, Negri A, Bisleri G , et al. Is total arterial myocardial revascularization with composite grafts a safe and useful procedure in the elderly?. Eur J Cardiothorac Surg 2003; 23 (5) 657-664 , discussion 664
  • 15 Calafiore AM, Contini M, Vitolla G , et al. Bilateral internal thoracic artery grafting: long-term clinical and angiographic results of in situ versus Y grafts. J Thorac Cardiovasc Surg 2000; 120 (5) 990-996
  • 16 Sakaguchi G, Tadamura E, Ohnaka M, Tambara K, Nishimura K, Komeda M. Composite arterial Y graft has less coronary flow reserve than independent grafts. Ann Thorac Surg 2002; 74 (2) 493-496
  • 17 Dion R, Glineur D, Derouck D , et al. Long-term clinical and angiographic follow-up of sequential internal thoracic artery grafting. Eur J Cardiothorac Surg 2000; 17 (4) 407-414
  • 18 Head SJ, Mack MJ, Holmes Jr DR , et al. Incidence, predictors and outcomes of incomplete revascularization after percutaneous coronary intervention and coronary artery bypass grafting: a subgroup analysis of 3-year SYNTAX data. Eur J Cardiothorac Surg 2012; 41 (3) 535-541