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Synlett 2019; 30(02): 181-184
DOI: 10.1055/s-0037-1610308
DOI: 10.1055/s-0037-1610308
letter
Ph3P/I–-Promoted Dichlorination or Dibromination of Epoxides with XCH2CH2X (X = Cl or Br)
We thank the National Basic Research Program of China (2015CB931903), the National Natural Science Foundation (21421002, 21472222, 21502214, 21672242, 81273537), the Chinese Academy of Sciences (XDA02020105, XDA02020106), the Key Research Program of Frontier Sciences (CAS) (QYZDJSSW-SLH049), the Key Project of Hunan Province Science and Technology Department (2016DK2001), the Key Project of Hunan Provincial Education Department (No. 17A190), the Zhengxiang Scholar Program of the University of South China, Hunan Provincial Hengyang City Joint Fund (2017JJ4050), and the Key Project of Hengyang Science and Technology Department(2017KJ166) for financial support.
Further Information
Publication History
Received: 03 September 2018
Accepted after revision: 30 September 2018
Publication Date:
19 December 2018 (online)
Abstract
Ph3P/I–-promoted dichlorination and dibromination of epoxides by using XCH2CH2X (X = Cl or Br) as the halogen source and reaction solvent is described. All reagents are widely available and easy to handle, and mild conditions and operational simplicity make this protocol attractive.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610308.
- Supporting Information
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