Quantitative Belastungs-Szintigraphie des Myokards mit ²⁰¹Tl — Methodik und Normal verhalten

Zusammenfassung

Bei 20 Normalpersonen wurde eine quantitative Myokardszintigraphie nach maximaler Belastung und nach zweistündiger Ruhe durchgeführt. Es wurden eine bewegliche Anger-Kamera mit Niederenergie-Kollimator und ein Data-General- Computer mit einer 128 x 128 Matrix verwendet. Die quantitative Analyse der Daten wurde mittels eines 14-Halbseg- ment-Modells durchgeführt. Quantitative Normalwerte nach Belastung und nach Umverteilung der Aktivität während der Ruhe werden vorgelegt.

Summary

Quantitative myocardial scintigraphy was performed in 20 normal individuals after maximum exercise and after two hours of rest. A mobile Anger camera with converging collimator and a Data-General computer with a 128 x 128 matrix were used. Quantitative analysis of data was performed on the basis of a 14-halfsegment model. Quantitative normal values after exercise and after redistribution of activity during rest are presented.

• Literatur

• 1 Büll U, Strauer BE, Bürger S, Witte J, Niendorf HP. Effects of physical stress and pharmalogically induced coronary dilation on myocardial and non-myocardial 20lTl-uptake. Eur. J. nucl. Med. 3: 19-27 1978;
• 2 Cook D J, Bailey I, Strauss HW, Rouleau J, Wagner HN, Pitt B. Thallium-201 for myocardial imaging: appearance of the normal heart. J. nucl. Med. 17: 583-589 1976;
• 3 Emrich D, Rentrop P, Facorro L, Karsch R, Schicha H, Carstens B, Kreuzer H. Limitations of Thallium-201 scintigraphy for evaluation of chronic ischemic heart disease. 2. Internat. Congr. World Fed. Nucl. Med. and Biol., Washington, Sept. 1978.
• 4 Goris M L, Daspit SG, McLaughlin P, Kriss JP. Interpolative background subtraction. J. nucl. Med. 17: 744-747 1976;
• 5 Graham L S, Poe ND, Robinson GD. Collimation for imaging the myocardium. J. nucl. Med. 17: 719-723 1976;
• 6 Groch M W, Lewis GK. Thallium-201: Scintillation camera imaging considerations. J. nucl. Med. 17: 142-145 1976;
• 7 Hamilton GW, Trobaugh GB, Ritchie JL, Williams DL, Weaver WD, Gould KL. Myocardial imaging with intravenously injected Thallium-201 in patients with suspected coronary artery disease. Amer. J. Cardiol. 39: 347354 1977;
• 8 Kawana M, Krizek H, Porter J, Lathrop D, Charleston D, Harper PV. Use of Tl-199 as a potassium analog in scanning. J. nucl. Med. 11: 333 (Abstr.) 1970;
• 9 Lebowitz E, Greene MW, Fairchild R, Bradley-Moore PR, Atkins HL, Ansari AN, Richards P, Belgrave E. Thallium-201 for medical use. 1. J. nucl. Med. 16 (15) 1-155 1975;
• 10 Lenaers A, Block P, van Thiel E, Labedelle M, Becquevort P, Erbsmann F, Ermans AM. Segmental analysis of TI-201 stress myocardial scintigraphy. J. nucl. Med. 18: 509-516 1977;
• 11 Luig H, Lahne R, Domovitz S. Ein Datensystem für kardiologische Untersuchungen mit einer Gamma-Kamera. In: Medizinische Physik (Ed.: W.J. Lorenz) Band II, pp. 99-112, de Gruyter, Berlin 1977.
• 12 Lusted LB. General problems in medical decision making with comments on ROC analysis. Sem. nucl. Med. 8: 299-308 1978;
• 13 Meade R C, Bamrah VS, Horgan JD, Ruetz PP, Kronenwetter C, Yeh E-L. Quantitative methods in the evaluation of Thallium-201 myocardial perfusion images. J. nucl. Med. 19: 1175-1178 1978;
• 14 Moyer RA. A low energy multihole converging collimator compared with a pinhole collimator. J. nucl. Med. 15: 59-64 1974;
• 15 Narahara K A, Hamilton GW, Williams DL, Gould KL. Myocardial imaging with Thallium-201: An experimental model for analysis of the true myocardial and background image components. J. nucl. Med. 18: 781-786 1977;
• 16 Nishiyama H, Romhilt DW, Williams CC, Adolph RJ, Sodd VJ, Blue JW, Lewis JT, Gabel M, van der Bel-Kahn JM. Collimator evaluation for Tl-201 myocardial imaging. J. nucl. Med. 19: 1067-1073 1978;
• 17 Pitt B, Strauss HW. Myocardial imaging in the noninvasive evaluation of patients with suspected ischemic heart disease. Amer. J. Cardiol. 37: 797-806 1976;
• 18 Prokop K, Strauss HW, Shaw J, Pitt B, Wagner HN. Comparison of Regional Myocardial Perfusion Determined by Ionic Potassium-43 to That Determined by Microspheres. Circulation 50: 978-984 1974;
• 19 Rentrop P, Karsch R, Nitsche K. Ischemic segment and left ventricular function during exercise angina. Clin. Cardiol. 1: 22-30 1978;
• 20 Schicha H, Rentrop P, Facorro L, Karsch R, Blanke H, Kreuzer H, Emrich D. Ergebnisse der quantitativen Myokardszintigraphie mit Thallium-201 in Ruhe und unter maximaler Belastung. Kritische Analyse des prädiktiven Wertes und der klinischen Anwendung. Z. Kardiol. (im Druck, 1979).
• 21 Strauss H W, Pitt B. Thallium-201 as a myocardial imaging agent. Sem. nucl. Med. 7: 49-58 1977;
• 22 Verani M S, Marcus ML, Razzak MA, Ehrhardt JC. Sensitivity and specificity of Thallium-201 perfusion scintigrams under exercise in the diagnosis of coronary artery disease. J. nucl. Med. 19: 773-782 1978;