Infektionen und Infektions-prävention bei Multipler Sklerose

Zusammenfassung

Der Artikel geht einleitend auf ätiopathologische Aspekte von Infektionen im Rahmen der Multiplen Sklerose (MS) ein. Nachfolgend werden infektiologische Risiken und Komplikationen im Zusammenhang mit immunmodulierenden MS-Therapeutika unter besonderer Berücksichtigung neu verfügbarer Behandlungsoptionen zusammengefasst und Empfehlungen zur Infektionsprävention unter diesen Therapien gegeben. Abschließend erfolgt die Diskussion folgender klinisch relevanter Probleme: generelle Impfempfehlung, Sicherheit von Impfungen und Kontrolle des Impferfolges bei MS.

Summary

We initially discuss aetiological and pathological aspects of infections in the context of multiple sclerosis. Disease modifying treatment can be associated with serious infections. Relevant issues concerning prevention and management of treatment associated infections with special focus on newly available treatment options are summarized. To address clinical relevant topics, general vaccine recommendations are adapted to compile with safety and efficacy in patients with multiple sclerosis.

Schlüsselwörter

Multiple Sklerose - Infektionen - Immuntherapien - Impfungen

Keywords

Multiple sclerosis - infections - disease modifying treatment - vaccinations

^* Beide Autoren haben gleichwertig zu dieser Publikation beigetragen.

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