Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00035037.xml
Download PDF
Methods Inf Med 1993; 32(02): 120-130
DOI: 10.1055/s-0038-1634904
DOI: 10.1055/s-0038-1634904
Original Article
Automatic Knowledge Acquisition from MEDLINE
This work was supported in part by NLM Training Grant T15-LM07037-4, UMLS Contract N01-LM-8-3513, and an equipment grant from the Hewlett-Packard Corporation. The authors wish to acknowledge Dr. Henry J. Lowe, M. D. for the data structures used to manage the MeSH terms and Ms. Laurie J. Hassan for invaluable programming assistance. The authors thank Ms. Leslie Juceam and Dr. George Hripcsak for editorial advice.
Further Information
Publication History
Publication Date:
08 February 2018 (online)
Abstract:
Construction of medical knowledge bases for use in expert systems is an arduous task. We propose a procedure for obtaining medical knowledge via automated analysis of citations found in the National Library of Medicine’s Medline ® database. In this method, simple pattern of keywords and subheading co-occurrences are detected in the keyword descriptor portion of the citations. Each pattern corresponds to a fact, expressed as a semantic relationship between medical concepts. We have constructed a set of 504 pattern-matching rules and applied it to a set of 673 Medline ® citations to produce 2,795 such facts. The results are presented of an analysis of the syntactic and semantic features of these facts to understand the kinds of knowledge than can be obtained through our method and speculate on the potential uses and pitfalls for knowledge of this type.
-
REFERENCES
- 1 Miller RA, Pople HE, Myers JD. INTER-NIST-I: An experimental computer-based diagnostic consultant for general internal medicine. N Engl J Med 1982; 307: 468-76.
- 2 Barnett GO, Cimino JJ, Hupp JA, Hoffer EP. DXplain - An evolving diagnostic decision-support system. J Am Med Assoc 1987; 258: 67-74.
- 3 Cole WG, Michael PA, Stewart JG, Blois MS. Automatic classification of medical text: The influence of publication form. In: Proceedings of the Twelfth Annual Symposium on Computer Applications in Medical Care. Greenes RA. (ed). New York: IEEE Computer Society Press; 1988: 196-200.
- 4 Rennels GD, Shortliffe EH, Stockdale FE, Miller PL. A computational model of reasoning from the medical literature. Comput Meth Prog Biomed 1987; 24: 139-49.
- 5 Bachrach CA, Charen T. Selection of MEDLINE contents, the development of its thesaurus, and the indexing process. Med Inform 1978; 03: 237-54.
- 6 National Library of Medicine, Library Operations. Medical Subject Headings. Bethesda, Md: National Library of Medicine; 1992
- 7 Powsner SM, Riely CA, Barwick KW, Morrow JS, Miller PL. Automated bibliographic retrieval based on current topics in hepatology: Hepatopix. Comput Biomed Res 1989; 22: 552-64.
- 8 Cimino JJ, Mallon LJ, Barnett GO. Automated extraction of medical knowledge from MEDLINE citations. In: Proceedings of the Twelfth Annual Symposium on Computer Applications in Medical Care. Greenes RA. (ed). New York: IEEE Computer Society Press; 1988: 180-4.
- 9 Harris Z. Language and Information. New York: Columbia University Press; 1988
- 10 Walton JD, Musen MA, Combs DM, Lane CD, Shortliffe EH, Fagan LM. Graphical access to medical expert systems: III. Design of a knowledge acquisition environment. Meth Inform Med 1987; 26: 78-88.
- 11 Shahsavar N, Gill H, Wigertz O, Frostell C, Matell G, Ludwigs U. KAVE: a tool for knowledge acquisition to support artificial ventilation. Comput Meth Prog Biomed 1991; 34: 115-23.
- 12 Warner HR, Haug P, Bouhaddou O, Lincoln M, Warner Jr H, Sorenson D, Williamson JW, Chinli F. ILIAD as a expert consultant to teach differential diagnosis. In: Proceedings of the Twelfth Annual Symposium on Computer Applications in Medical Care. Greenes RA. (ed). New York: IEEE Computer Society Press; 1988: 371-6.
- 13 Chowdhury S, Bodemar G, Haug P, Babic A, Wigertz O. Methods for knowledge extraction from a clinical database on liver diseases. Comput Biomed Res 1991; 24: 530-48.
- 14 Giuse DA, Giuse NB, Miller RA. Towards computer assisted maintenance of medical knowledge bases. Artif Intell Med 1990; 02: 21-33.
- 15 Giuse DA, Giuse NB, Miller RA. Heuristic determination of quantitative data for knowledge acquisition in medicine. Comput Biomed Res 1991; 24: 261-72.
- 16 Johnson SB, Gottfried M. Sublanguage analysis as a basic for a controlled medical vocabulary. In: Proceeding of the Thirteenth Annual Symposium on Computer Applications in Medical Care. Kingsland LC. (ed). New York: IEEE Computer Society Press; 1989: 519-23.
- 17 Lindberg DA, Schoolman HM. The National Library of Medicine and medical informatics. West J Med 1986; 145: 786-90.
- 18 Lowe HJ, Barnett GO, Scott J, Mallon L, Ryan-Blewett D. Remote Access Micro-MeSH: Evaluation of a microcomputer system for searching the MEDLINE database. In: Proceedings of the Thirteenth Annual Symposium on Computer Applications in Medical Care. Kingsland LC. (ed). New York: IEEE Computer Society Press; 1989: 445-7.
- 19 Kok FJ, Schrijver J, Hofman A. et al. Low vitamin B6 status in patients with acute myocardial infarction. Am J Cardiol 1989; 63: 513-6.
- 20 Barr CE, Komorowski HJ, Pattison-Gordon E, Greenes RA. Conceptual modeling for the Unified Medical Language System. In: Proceedings of the Twelfth Annual Symposium on Computer Applications in Medical Care. Greenes RA. (ed). New York: IEEE Computer Society Press; 1988: 148-51.
- 21 Humphreys BL, Lindberg DAB. Building the Unified Medical Language System. In: Proceedings of the Thirteenth Annual Symposium on Computer Applications in Medical Care. Kingsland LC. (ed). New York: IEEE Computer Society Press; 1989: 475-80.
- 22 McCray A. The UMLS Semantic Network. In: Proceedings of the Thirteenth Annual Symposium on Computer Applications in Medical Care. Kingsland LC. (ed). New York: IEEE Computer Society Press; 1989: 503-7.
- 23 Greenes RA, Tarabar DB, Krauss M. et al. Knowledge management as a decision support method: A diagnostic workup strategy application. Comput Biomed Res 1989; 22: 113-35.
- 24 Cimino JJ, Elkin PL, Barnett GO. As we may think: the Concept Space and medical hypertext. Comput Biomed Res 1992; 25: 238-63.
- 25 Musen MA, van der Lei J. Knowledge engineering for clinical consultation programs: Modeling the application area. Meth Inform Med 1989; 28: 28-35.