Abstract.
Many studies have been done on the respiratory and the cardiovascular system. Among
them, only a few are on the interaction of these two physiologic systems. To explore
the mechanism of the integration of these two physiological systems, computer simulation
has been done; we report the preliminary results obtained in our laboratory. In this
study, a mathematical model of the cardiovascular system integrated with the respiratory
mechanical system has been established. The model is based on our previous work on
cardiovascular modeling. The previous lumped lungi model has been replaced by a multielement
model with more detail. Inter- thoracic and abdominal pressures are modeled as external
pressure sources on the related cardiovascular elements. Using this model, a sequence
of simulation studies have been carried out. Different respiratory modes have been
simulated and the different effects are observed in the simulation results. The results
indicate that by following a certain respiratory pattern, the circulation status can
be improved. These results agree with clinical observations.Keywords: Mathematical Model, Respiration Mode, Cardiovascular System, Computer Simulation,
Interaction
Keywords:
Mathematical Model - Respiration Mode - Cardiovascular System - Computer Simulation
- Interaction