The Effect of Human Platelets on Lipolytic Activity in Plasma

Harald Vik-Mo

doi:10.1055/s-0038-1647845

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1975; 33(03): 519-527
DOI: 10.1055/s-0038-1647845

Original Article

Schattauer GmbH

The Effect of Human Platelets on Lipolytic Activity in Plasma

Harald Vik-Mo^*

¹Department of Medicine (Chief: Professor A. Nordøy), Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway

› Author Affiliations

Abstract

Summary

A method for assay of lipolytic activity in platelet-poor plasma (PPP), platelet-rich plasma (PRP) and washed human platelets is presented. The lipolytic activity in PRP was about twice the activity in PPP. A significant correlation between lipolysis in platelets and platelet number was established. Molar sodium chloride strongly inhibited lipolytic activity in platelets and a washing procedure did not significantly change the lipolysis. The results indicate that a lipoprotein lipase is bound to human platelets and may play a role in metabolism of triglyceride in platelets.

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References

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