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Thromb Haemost 1975; 34(03): 734-739
DOI: 10.1055/s-0038-1651466
DOI: 10.1055/s-0038-1651466
Original Article
Clinical Observations and their Relationship to Laboratory Findings in the Haemophilias
Further Information
Publication History
Received
25 May 1975
Accepted
16 July 1975
Publication Date:
02 July 2018 (online)
Summary
Continuous observations in school terms have been made on the frequency of spontaneous bleeding episodes in a group of adolescent boys suffering from haemophilia (39 cases), Christmas disease (9 cases), and von Willebrand’s disease (2 cases). The observations suggest that in haemophilia other factors, besides the deficient factor VIII, affect the bleeding frequency. In the two boys with von Willebrand’s disease, the lower level of factor VIII was associated with the milder symptoms; whereas in boys with Christmas disease clinical severity and laboratory results seemed to be correlated.
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References
- 1 Laurell C. B. 1966; Quantitative Estimation of Proteins by Electrophoresis in Agarose Gel Containing Antibodies. Analytical Biochemistry 15: 45.
- 2 Rainsford S. G, and Hall Angela. 1973; A Three-Year Study of Adolescent Boys Suffering from Haemophilia and Allied Disorders. British Journal of Haematology 24: 539.
- 3 Rainsford S. G, Richardson Dorothy, and Shaw C. S. 1974; Plasma-Cortisol Levels and the Frequency of Bleeding in Haemophilia. Clinica Chimica Acta 53: 351.
- 4 Walsh P. N, Rainsford S. G, and Biggs Rosemary. 1973; Platelet Coagulant Activities and Clinical Severity in Haemophilia. Thrombosis et Diathesis Haemorrhagica 29: 722.