Low-Volume Cardioplegia and Myocardial Protection in Coronary Artery Bypass Graft Surgery

Samuel Tschopp; Friedrich Eckstein; Peter Matt

doi:10.1055/s-0038-1667322

The Thoracic and Cardiovascular Surgeon, Table of Contents

Thorac Cardiovasc Surg 2019; 67(06): 484-487
DOI: 10.1055/s-0038-1667322

Short Communication

Georg Thieme Verlag KG Stuttgart · New York

Low-Volume Cardioplegia and Myocardial Protection in Coronary Artery Bypass Graft Surgery

Authors

Samuel Tschopp

¹Department of Cardiac Surgery, University Hospital Basel, Basel, Switzerland
Friedrich Eckstein

¹Department of Cardiac Surgery, University Hospital Basel, Basel, Switzerland
Peter Matt

²Department of Cardiac Surgery, Herzzentrum Luzern, Luzern, Switzerland

Abstract

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Abstract

We studied myocardial protection during coronary artery bypass graft surgery using low-volume cardioplegia (Cardioplexol) and minimal extracorporeal circulation (MECC) for different types of coronary artery diseases. In total, 426 consecutive patients were included and divided into four groups: those with left main stem stenosis (n = 45), those with three-vessel disease (n = 200), those with both (n = 141), and those with neither (n = 40). The peak postoperative myocardial markers and 30-day mortality were analyzed. Both myocardial markers and 30-day mortality were significantly elevated in patients with isolated main stem stenosis. We conclude that the use of low-volume cardioplegia and MECC is safe. However, patients with underlying isolated left main stem stenosis might be less protected.

Keywords

coronary artery bypass graft surgery - CABG - myocardial protection - cardioplegia - ischemia/reperfusion - outcomes - surgery - complications

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References

References
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