Abstract
Septopreoptic holoprosencephaly (HPE) is a type of HPE characterized by failure of
separation of the septal and preoptic regions. Vascular anomalies associated with
septopreoptic HPE include twig-like cerebral vessels and azygos anterior cerebral
artery, the latter common to all forms of HPE. Here, we describe an 8-year-old boy
presenting with developmental delay and abnormal movements who was found to have septopreoptic
HPE associated with persistent trigeminal artery in magnetic resonance neuroimaging.
This persistence of fetal trigeminal artery in HPE provides a further understanding
of the pathogenesis of HPE.
Keywords
persistent trigeminal artery - septopreoptic holoprosencephaly - MRI - developmental
delay
