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Thorac Cardiovasc Surg 2021; 69(06): 504-510
DOI: 10.1055/s-0040-1713351
Original Cardiovascular

Successful Heart Transplantation after Cardiopulmonary Resuscitation of Donors

Arash Mehdiani   *
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Moritz Benjamin Immohr   *
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Nihat Firat Sipahi
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Charlotte Boettger
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Hannan Dalyanoglu
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Daniel Scheiber
2   Department of Cardiology, Pulmonology and Vascular Medicine, Heinrich-Heine-University Medical School, Moorenstrasse 5, Duesseldorf, Germany
,
Ralf Westenfeld
2   Department of Cardiology, Pulmonology and Vascular Medicine, Heinrich-Heine-University Medical School, Moorenstrasse 5, Duesseldorf, Germany
,
Hug Aubin 
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Artur Lichtenberg
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Udo Boeken 
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
,
Payam Akhyari 
1   Department of Cardiac Surgery, University Hospital Duesseldorf, Duesseldorf, Germany
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Erratum to: Successful Heart Transplantation after Cardiopulmonary Resuscitation of DonorsThorac Cardiovasc Surg 2021; 69(06): e1-e2
DOI: 10.1055/s-0040-1716567

Abstract

Background Heart transplantation (HTx) is the best therapy for end-stage heart failure. Unfortunately, death on the waiting list remains a problem. Decreasing the number of rejected organs could increase the donor pool.

Methods A total of 144 patients underwent HTx at our department between 2010 and 2019. Of them, 27 patients received organs of donors with cardiopulmonary resuscitation (CPR) prior to organ donation (donor CPR) and were compared with patients who received organs without CPR (control; n = 117).

Results We did not observe any disadvantage in the outcome of the donor CPR group compared with the control group. Postoperative morbidity and 1-year survival (control: 72%; donor CPR: 82%; p = 0.35) did not show any differences. We found no impact of the CPR time as well as the duration between CPR and organ donation, but we found an improved survival rate for donors suffering from anoxic brain injury compared with cerebral injury (p = 0.04).

Conclusions Donor organs should not be rejected for HTx due to resuscitation prior to donation. The need for CPR does not affect the graft function after HTx in both short- and mid-term outcomes. We encourage the use of these organs to increase the donor pool and preserve good results.

Keywords

heart transplantation - cardiopulmonary resuscitation - donor - marginal organ

* Both authors share first authorship.




Publication History

Received: 29 December 2019

Accepted: 27 April 2020

Article published online:
16 July 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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