Updates in Diabetic Wound Healing, Inflammation, and Scarring

Nina Dasari; Austin Jiang; Anna Skochdopole; Jayer Chung; Edward M. Reece; Joshua Vorstenbosch; Sebastian Winocour

doi:10.1055/s-0041-1731460

Seminars in Plastic Surgery, Table of Contents

Semin Plast Surg 2021; 35(03): 153-158
DOI: 10.1055/s-0041-1731460

Review Article

Updates in Diabetic Wound Healing, Inflammation, and Scarring

Authors

Nina Dasari

¹Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
Austin Jiang

¹Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
Anna Skochdopole

¹Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
Jayer Chung

²Division of Vascular Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
Edward M. Reece

¹Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas

³Division of Plastic Surgery, Department of Surgery, Texas Children's Hospital, Houston, Texas
Joshua Vorstenbosch

⁴Division of Plastic Surgery, Department of Surgery, McGill University, Montreal, Canada
Sebastian Winocour

¹Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas

Abstract

Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.

Keywords

diabetes - wound healing - inflammation - scarring

Full Text

References

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