J Pediatr Genet
DOI: 10.1055/s-0041-1739386
Case-Based Review

Matthew-Wood Syndrome in Monochorionic, Diamnionic Twins

Irina Geiculescu
1   Department of Pediatrics, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States
,
2   Division of Neonatology, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States
,
Laurie Demmer
3   Division of Genetics, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States
,
Ronald Sutsko
2   Division of Neonatology, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States
,
Graham Cosper
4   Department of Surgery, Atrium Healthcare, Charlotte, North Carolina, United States
,
James E. Jones
2   Division of Neonatology, Levine Children's Hospital, Atrium Healthcare, Charlotte, North Carolina, United States
› Author Affiliations
Funding None.

Abstract

Matthew-Wood syndrome represents a rare genetic disorder characterized by diaphragmatic defects, pulmonary hypoplasia, micro- or anophthalmia, and cardiac defects. Most cases are lethal with very few infants living beyond a few years of life. Siblings with this diagnosis have been reported but never twins. In this article, we provided a review and discussion of this syndrome following its presentation in monochorionic, diamnionic twin females.

Note

Informed consent was obtained from both parents for the publication of this report. The parents wished that their daughters would advance the scientific community.




Publication History

Received: 16 March 2021

Accepted: 29 September 2021

Article published online:
09 November 2021

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