Drug Res (Stuttg) 2017; 67(05): 266-270
DOI: 10.1055/s-0042-113459
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

Preparation and Characterization of Gold Nanoparticles in the Presence of Citrate and Soybean Seed Extract in an Acidic Conditions

Ebrahim Izadi
1   Department of Mechanical Engineering, University of Tabriz, Tabriz, Iran
6   Universal Scientific Education and Research Network (USERN), Tabriz, Iran
,
Ali Rasooli
1   Department of Mechanical Engineering, University of Tabriz, Tabriz, Iran
,
Abolfazl Akbarzadeh
2   Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3   Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
6   Universal Scientific Education and Research Network (USERN), Tabriz, Iran
,
Soodabeh Davaran
4   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2   Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3   Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5   Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Medical, University of Tabriz, Tabriz, Iran
› Author Affiliations
Further Information

Publication History

received  17 June 2016

accepted 22 July 2016

Publication Date:
17 February 2017 (online)

Abstract

Through the present study, an eco-friendly method was used to synthesize the gold nanoparticles (GNPs) by using the sodium citrate and extract of the soybean seed as reducing the agents at PH 3. X-Ray diffraction (XRD) method was used to evaluate the crystal structure of as-synthesized NPs and it’s revealed that this method leads to well crystallized GNPs. In order to determine the particle size and their distribution, field emission scanning microscopy (FE-SEM) and dynamic light scattering (DLS) were used. The results showed that, the average particle size distribution of synthesized GNPs in solutions containing of the soybean extract and 1% citrate at PH 3 is about 109.6 and 140.9 nm, respectively. Also, we find that the average size of GNPs is 40 and 33 nm from solutions of citrate and soybean extract, respectively. It was concluded that using the extract of soybean seeds as reducing agent can lead to GNPs with small size and narrow size distribution.

 
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