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Thorac Cardiovasc Surg 2022; 70(06): 458-466
DOI: 10.1055/s-0042-1749686
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Rationale and Initiative of the Impella in Cardiac Surgery (ImCarS) Register Platform

Authors

  • Bernd Niemann

    1   Department of Cardiovascular Surgery, University Hospital Giessen, Germany

  • Christian Stoppe

    2   Department of Anesthesiology and Intensive Care Medicine, University Hospital Würzburg, Würzburg, Bavaria, Germany
    3   Abiomed, Abiomed, Danvers, Massachusetts, United States

  • Michael Wittenberg

    4   Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Hessia, Germany

  • Susanne Rohrbach

    5   Institute of Physiology, Justus-Liebig-University Giessen, Giessen, Hessen, Germany

  • Diyar Saeed

    6   Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany

  • Michael Billion

    7   Department of Cardiac Surgery, Schüchtermann Hospital Bad Rothenfelde, Bad Rothenfelde, Niedersachsen, Germany

  • Evgenij Potapov

    8   Department of Cardiac Surgery, Deutsches Herzzentrum Berlin Ringgold Standard Institution, Berlin, Berlin, Germany

  • Mehmet Oezkur

    9   Department of Cardiac and Vascular Surgery, University of Mainz, Mainz, Germany

  • Payam Akhyari 

    10   Department of Cardiac Surgery, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany

  • Bastian Schmack

    11   Department of Cardiac Surgery, University of Essen, Essen, Germany

  • David Schibilsky

    12   Department of Cardiac Surgery, University of Freiburg, Freiburg, Germany

  • Alexander M. Bernhardt 

    13   Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany

  • Jan D. Schmitto

    14   Department of Cardiac-, Thoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany

  • Christian Hagl

    15   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, München, Germany

  • Paolo Masiello

    16   Department of Cardiac Surgery, San Giovanni di Dio e R.A. Hospital, Salerno, Salerno, Italy

  • Andreas Böning

    1   Department of Cardiovascular Surgery, University Hospital Giessen, Germany

Funding The ImCarS registry is funded by Abiomed.
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Erratum to: Rational and Initiative of the Impella in Cardiac Surgery (ImCarS) Register PlatformThorac Cardiovasc Surg 2022; 70(06): e1-e1
DOI: 10.1055/s-0042-1755310

Abstract

Objectives Cardiac support systems are being used increasingly more due to the growing prevalence of heart failure and cardiogenic shock. Reducing cardiac afterload, intracardiac pressure, and flow support are important factors. Extracorporeal membrane oxygenation (ECMO) and intracardiac microaxial pump systems (Impella) as non-permanent MCS (mechanical circulatory support) are being used increasingly.

Methods We reviewed the recent literature and developed an international European registry for non-permanent MCS.

Results Life-threatening conditions that are observed preoperatively often include reduced left ventricular function, systemic hypoperfusion, myocardial infarction, acute and chronic heart failure, myocarditis, and valve vitia. Postoperative complications that are commonly observed include severe systemic inflammatory response, ischemia-reperfusion injury, trauma-related disorders, which ultimately may lead to low cardiac output (CO) syndrome and organ dysfunctions, which necessitates a prolonged ICU stay. Choosing the appropriate device for support is critical. The management strategies and complications differ by system. The “heart-team” approach is inevitably needed.

However despite previous efforts to elucidate these topics, it remains largely unclear which patients benefit from certain systems, when is the right time to initiate (MCS), which support system is appropriate, what is the optimal level and type of support, which therapeutic additive and supportive strategies should be considered and ultimately, what are the future prospects and therapeutic developments.

Conclusion The European cardiac surgical register ImCarS has been established as an IIT with the overall aim to evaluate data received from the daily clinical practice in cardiac surgery. Interested colleagues are cordially invited to join the register.

Clinical registration number: DRKS00024560.

Positive Ethics Vote: AZ 246/20 Faculty of Medicine, Justus-Liebig-University-Gießen.

Keywords

Impella - ECMO - cardiac support - cardiac surgery

Authors' Contributions

B.N., S.R., A.B., and C.S. have contributed to conception, data collection, writing, and proofreading of the manuscript., M.W. has contributed toward conception and proofreading, D.S. contributed to writing and proofreading the manuscript. M.B., E.P., M.O., P.A., B.S., D.S., A.M.B., J.D.S., and P.M. have contributed to proofreading. All authors are investigators of the ImCarS registry.

In addition to presenting the current data situation, we would like to present the ImCarS Register in Europe and invite the readers in Europe to cooperate. This manuscript describes review data. All authors approved the manuscript and this submission. Our local ethics committee has approved our study and register platform.


Supplementary Material



Publication History

Received: 01 April 2022

Accepted: 07 April 2022

Article published online:
11 July 2022

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