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DOI: 10.1055/s-0043-1765055
Endoscopic vacuum therapy for the treatment of upper gastrointestinal defects. Results of a Spanish multicenter registry
Authors
Aims To evaluate the effectiveness and safety of endoscopic vacuum therapy (EVT) for the treatment of upper gastrointestinal (GI) defects. To assess risk factors associated with EVT failure and in-hospital mortality in these patients.
Methods Retrospective study of a Spanish multicenter registry where all patients treated with EVT were consecutively included between November 2018 and March 2022.
Results 102 patients from 18 hospitals were included, 89 (87.3%) with an anastomotic dehiscence and 13 (12.7%) with an acute perforation. 20 (19.6%) patients were reoperated and 19 (18.6%) received an esophageal stent as primary treatment before starting EVT. The average delay in the onset of EVT was 13 days (IQR 7-28). Intracavitary EVT was used in 66 (64.7%) cases and intraluminal EVT in 36 (35.3%). The average number of sponges was 5 (IQR 3-7). The median duration of EVT was 19 days (IQR 11-27). Closure of the defect was achieved in 84 cases (82%). 6 patients (5.9%) presented some adverse event related to EVT: 1 fatal bleeding, 1 jejunal perforation and 4 minor events. 11 (10.7%) patients presented anastomotic strictures. In-hospital mortality was 12.7% (n=13). The delay in the initiation of EVT and the development of a fistula during therapy were independent predictors of EVT failure. EVT failure and the development of pneumonia were independent predictors of in-hospital mortality.
Conclusions EVT is effective and safe for treating upper GI defects. Early use could improve the effectiveness of the therapy and therefore reduce the in-hospital mortality of these patients.
Conflicts of interest
A. M. de Lacy is a consultant for B. BraunA. Cardenas is a consultant for B. Braun and Boston ScientificA. Ibarzabal is a consultant for B. BraunD. Momblan is a consultant for B. BraunOriol Sendino is a consultant for B.Braun
Publikationsverlauf
Artikel online veröffentlicht:
14. April 2023
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