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Clin Colon Rectal Surg 2001; 14(1): 007-014
DOI: 10.1055/s-2001-13137
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Perioperative Antibiotics

Scott Chapman, Frank J. Harford
  • 1Division of Colon and Rectal Surgery, Loyola University, Maywood, IL
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Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

The use of both and oral and systemic antibiotics appears to decrease the rate of postoperative wound infection. Most but not all the studies comparing oral antibiotics alone versus oral plus parenteral antibiotics show a significant reduction in wound infection with a combination of the two. Topical antibiotics seem to confer no advantage over preoperative systemic antibiotics. The use of other adjuvants to prevent wound infections such as the use of filtered blood supplemental oxygen and immunostimulation is discussed.

KEYWORD

Perioperative antibiotics - wound infection - bowel preparation

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