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DOI: 10.1055/s-2001-14503
Reizdarmsyndrom (RDS) - Was ist diagnostisch und therapeutisch möglich und nützlich ?
Irritable bowel syndrome: what is possible and helpful in its diagnosis and treatment?Publication History
Publication Date:
11 September 2002 (online)

Vorbemerkung
Im Gegensatz zu organischen, meist gut definierten gastroenterologischen Krankheitsbildern, wie z. B. dem Ulkusleiden und Morbus Crohn, mit klar umschriebenen diagnostischen und therapeutischen Handlungsanweisungen sind die funktionellen gastroenterologischen Störungen und Erkrankungen jeweils als Ergebnis von krankhaft veränderten Funktionen ohne Nachweis von biochemischen und/oder morphologischen Veränderungen, besonders für die Diagnosesicherung und Behandlungsstrategie schwer fassbar.
Dies trifft im besonderen Maße für das Reizdarmsyndrom (RDS) zu. In den letzten Jahren wurden von verschiedenen Fachgesellschaften mehrere Leitlinien zum Management des RDS publiziert wie der »Technical Review on IBS« aus den USA [9], die Revision des Rom-I-Projektes »The functional gastrointestinal disorders Rome II« [7] sowie der Konsensusbericht der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) 1999 [18] und »Guidelines of the Management of IBS der britischen Society of Gastroenterology« [23] .
Die vorliegende Übersichtsarbeit basiert im Wesentlichen auf den vor 2 Jahren erarbeiteten deutschen Leitlinien der DGVS unter Berücksichtigung neuerer Publikationen innerhalb der letzten 2 Jahre.
Literatur
- 1
Agreus L, Svärdsudd K, Nyren O, Tibblin G.
Irritable bowel syndrome
and dyspepsia in the general population: overlap and lack of stability
over time.
Gastroenterology.
1995;
109
671-80
MissingFormLabel
- 2
Allescher, HD, Adler G, Hartung J, Manns M P, Riemann J F, Wienbeck M, Classen M.
Prospektive
Epidemiologische Studie der Oberbauchschmerzen.
DMW.
1999;
15
443
MissingFormLabel
- 3
Bennett P, Wilkinson A.
A
comparsion of psychological and medical treatment of the irritable
bowel syndrome.
British J of Clin Psychology.
1985;
24
215-216
MissingFormLabel
- 4
Bensoussan A, Talley N J, Hing M. et al .
Treatment of irritable bowel syndrome with
Chinese herbal medicine. A randomized controlled study.
Jama.
1998;
280
1585-1589
MissingFormLabel
- 5
CannPA, Read N W, Holdsworth C D, Barends D.
Role
of loperamide and placebo in management of irritable bowel syndrome.
Dig
Dis Sci.
1984;
29
239-247
MissingFormLabel
- 6
Delvaux M, Denis P, Allemand H. and the French Club of
Digestive Motility .
Sexual abuse is more frequently
reported by IBS patients than by patients with organic digestive
disease or controls. Results of a multicentre inquiry.
Eur
J Gastroenterol Hepatol.
1996;
9
345-352
MissingFormLabel
- 7 Drossman D A, Corazziari E, Talley N J, Thompson W G, Whitehead W E. Rome
II- The functional gastrointestinal disorders. Diagnosis, Pathophysiology
and Treatment: A multinational consensus. (Editors)
Allen press, ENC, Lawrence, KS 2000 (Second
Edition)
MissingFormLabel
- 8
Drossman D A, Leserman J, Nachman G, Li Z, Gluck H, Toomey T C, Mitchell C M.
Sexual and
physical abuse in women with functional organic disorders.
Ann
Int Med.
1990;
113
828-833
MissingFormLabel
- 9
Drossman D A, Li Z, Andruzzi E, Temple R D, Talley N J, Thompson W G, Whitehead W E, Janssens J, Funch-Jensen P. et al .
U.S.
householder survey on functional gastrointestinal disorders.
Dig
Dis Sci.
1993;
38
1569-1580
MissingFormLabel
- 10
Drossman D A, Whitehead W E, Camilleri M. for the American Gastroenterological Association Patient Care
Committee .
Irritable bowel syndrome: A technical review
for practice guideline development.
Gastroenterology.
1997;
112
2102-2137
MissingFormLabel
- 11
Edwards C A, Eastwood M A.
Comparison
of the effects of isphagula and wheat bran on rat caecal and colonic
fermentation.
Gut.
1992;
33
1229-1233
MissingFormLabel
- 12
Enck P, Kremer A, Kuhlbusch R, Nierderau C, Erckenbrecht J F, Berges W.
Prevalence
of lactose malabsorption among patients with functional bowel disorders.
Z
Gastroenterol.
1990;
28
239-241
MissingFormLabel
- 13
Enck P, Wienbeck M.
Epidemiology
and psychological factors of the irritable bowel syndrome.
Europ
J Gastroenterol Hepatol.
1993;
5
979-989
MissingFormLabel
- 14
Francis C Y, Whorwell P J.
Brain and
irritable bowel syndrome: time for reappraisal.
Lancet.
1994;
344
39-40
MissingFormLabel
- 15
Guthrie E, Creed F, Dawson D, Tomenson B.
A
controlled trial of psychologiacal treatment for the irritable bowel
syndrome.
Gastroenterology.
1991;
100
450-457
MissingFormLabel
- 16
Hamilton J W, Wagner J, Burdick B B, Bass P.
Clinical evaluation of methylcellulose
as a bulk laxative.
Dig Dis Sci.
1988;
33
993-998
MissingFormLabel
- 17
Holtmann G, Goebell H, Talley N J.
Functional
dyspepsia and irritable bowel syndrome: is there a common pathophysiological
basis ?.
Am J Gastroenterol.
1997;
92
954-959
MissingFormLabel
- 18
Hotz J, Enck P, Goebell H, Heymann-Mönnikes I, Holtmann G, Layer P.
Konsensusbericht:
Reizdarmsyndrom. Definition, Diagnosesicherung, Pathophysiologie
und Therapiemöglichkeiten. Konsensus der Deutschen Gesellschaft
für Verdauungs- und Stoffwechselkrankheiten.
Z
Gastroenterol.
1999;
37
685-700
MissingFormLabel
- 19
Madisch A, Holtmann G, Hotz J. et al .
Benefit of a herbal preparation in patients
with irritable bowel syndrome: results of a double-blind, randomized,
placebo-controlled multicenter trial.
Gastroenterology.
2000;
4
A4440
MissingFormLabel
- 20
Hotz J, Plein K.
Empfehlungen
zur Therapie des Colon irritabile.
Verdauungskrh.
1997;
15
196-199
MissingFormLabel
- 21
Hotz J, Plein K.
Wirkung
von Plantago-Samenschalen im Vergleich zu Weizenkleie auf Stuhlfrequenz
und Beschwerden beim Colon irritabile-Syndrom mit Obstipation.
Med
Klin.
1994;
89
645-651
MissingFormLabel
- 22
Ivey K W.
Are
anticholinergics of use in the irritable colon syndrome?.
Gastroenterol.
1975;
68
1300-1307
MissingFormLabel
- 23
Jones J, Boorman J, Cann P, Forbes A, Gomborone J, Heaton K. et al .
British
Society of Gastroenterology guidelines for the management of the
irritable bowel syndrome.
Gut.
2000;
ii1-ii19
(Suppl II) 4)
MissingFormLabel
- 24
Jones R, Lydeard S.
Irritable
bowel syndrome in the general population.
BMJ.
1992;
304
87-90
MissingFormLabel
- 25
Jones V A, MCLaughlan P, Shorthouse M, Workman E, Hunter J O.
Food
intolerance: a major factor in the pathogenesis of irritable bowel
syndrome.
Lancet.
1982;
2
1115-1117
MissingFormLabel
- 26
Kellow J E, Phillips S F.
Altered small
bowel motility in irritable bowel syndrome is correlated with symptoms.
Gastroenterology.
1987;
92
1885-1893
MissingFormLabel
- 27
Klein K B.
Controlled
treatment trials in the irritable bowel syndrome: a critique.
Gastroenterology.
1988;
95
232-241
MissingFormLabel
- 28
Lémann M, Dederding J P, Flourie B, Franchisseur C, Rambaud J C, Jian R.
Abnormal perception of
visceral pain in response to gastric distension in gastric idiopathic
dyspepsia. The irritable stomach syndrome.
Dig Dis Sci.
1991;
36
1249-1254
MissingFormLabel
- 29
Lembo T.
Fiber
and its effect on colonic function in health and disease.
Current
opinion in Gastroenterology.
1998;
14
1-5
MissingFormLabel
- 30
Lynch P M, Zamble E A.
A controlled
behavioral treatment study of irritable bowel syndrome.
Behavior
Therapy.
1989;
509-523
MissingFormLabel
- 31
Marteau P, Flourié B, Cherbut C, Corréze J L, Pellier P, Seylaz J, Rambaud J C.
Digestibility
and bulking effect of isphaghula husks in healthy humans.
Gut.
1994;
35
1747-1752
MissingFormLabel
- 32
McKendrick M W, Read N W.
Irritable bowel
syndrome - post salmonella infection.
J Infect.
1994;
29
1-3
MissingFormLabel
- 33
Neal K R, Hebden J, Spiller R.
Prevalence
of gastrointestinal symptoms six months after bacterial gastroenteritis
and risk factors for development of the irritable bowel syndrome:
postal survey of patients.
Brit Med J.
1997;
314
779-82
MissingFormLabel
- 34
Passaretti S, Tittobello A, Capozzi C, Verlinden M.
Cisapride accelerates
total intestinal transit in patients with irritable bowel syndrome-associated
constipation.
Progr Med.
1987;
43
121-129
MissingFormLabel
- 35
Poynard T, Naveau S, Mory B, Chaput J C.
Meta-analysis
of smooth muscle relaxants in the treatment of irritbale bowel syndrome.
Aliment
Pharm Ther.
1994;
8
499-410
MissingFormLabel
- 36
Richter J E, Barish C F, Castell D O.
Abnormal
sensory perception in patients with esophageal chest pain.
Gastroenterology.
1986;
91
845-852
MissingFormLabel
- 37
Van Outryve M, Milo R, Toussaint J. et al .
»Prokinetc« treatment
of constipation-predominant irritable bowel syndrome: a placebo-controlled
study of cisapride.
J Clin Gastroenterol.
1991;
13
49
MissingFormLabel
- 38
Whitehead W E, Crowell M D, Robinson J C, Heller B R, Schuster M M.
Effects
of stressful life events on bowel symptoms: subjects with irritable
bowel syndrome compared with subjects without bowel dysfunction.
Gut.
1992;
33
825-830
MissingFormLabel
- 39
Whitehead W E, Holtkoetter B, Enck P, Hoelzl R, Holmes K D, Anthony J, Shabsin H S, Schuster M M.
Tolerance
for rectosigmoid distention in irritable bowel syndrome.
Gastroenterology.
1990;
98
1187-1192
MissingFormLabel
- 40
Zwetschenbaum J F, Burakoff R.
Food allergy and the
irritable bowel syndrome.
Am J Gastroenterol.
1988;
83
901-904
MissingFormLabel
Korrespondenz
Prof. Dr. med. J. Hotz
Klinik für Gastroenterologie Allgemeines
Krankenhaus Celle
Siemensplatz 4
29223 Celle
Phone: 05141/721201
Fax: 05141/721209
Email: gastroenterologie@akh-celle.de