Endoscopy 2002; 34(1): 63-68
DOI: 10.1055/s-2002-19392
State of the Art Review

© Georg Thieme Verlag Stuttgart · New York

Inflammatory Bowel Disease

P.  Marteau1
  • 1Dept. of Gastroenterology, Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, and Paris V University, France
Further Information

Publication History

Submitted

Accepted after Revision

Publication Date:
14 August 2002 (online)

This article reviews a selection of 50 papers on inflammatory bowel disease published between April 2000 and June 2001. The new information summarized here includes: the discovery of the association of the NOD2 gene with Crohn's disease; the role of bacteria and the modulating effects of probiotics; the inverse association of appendectomy and ulcerative colitis; progress in imaging based on magnetic resonance imaging and leukocyte scintigraphy; assessment of the value of anti-Saccharomyces cerevisiae antibodies in the screening of inflammatory bowel disease and differentiation between ulcerative colitis and Crohn's disease; and risk factors and management of dysplasia and cancer. This article does not review all therapeutic aspects, but focuses on smoking cessation; anti-tumor necrosis factor antibody treatments; the usefulness of measuring erythrocyte 6-thioguanine metabolite levels to optimize purine analogue therapy; strictureplasty; and the long-term results of ileoanal anastomosis.

References

  • 1 Hugot J P, Chamaillard M, Zouali H. et al . Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.  Nature. 2001;  411 599-603
  • 2 Ogura Y, Bonen D K, Inohara N. et al . A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.  Nature. 2001;  411 603-606
  • 3 Hampe J, Cuthbert A, Croucher P J. et al . Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations.  Lancet. 2001;  357 1925-1928
  • 4 Laharie D, Debeugny S, Peeters M. et al . Inflammatory bowel disease in spouses and their offspring.  Gastroenterology. 2001;  120 816-819
  • 5 Pardi D S, Tremaine W J, Sandborn W J. et al . Early measles virus infection is associated with the development of inflammatory bowel disease.  Am J Gastroenterol. 2000;  95 1480-1485
  • 6 Morris D L, Montgomery S M, Thompson N P. et al . Measles vaccination and inflammatory bowel disease: a national British Cohort Study.  Am J Gastroenterol. 2000;  95 3507-3512
  • 7 Sutton C L, Kim J, Yamane A. et al . Identification of a novel bacterial sequence associated with Crohn's disease.  Gastroenterology. 2000;  119 23-31
  • 8 Masseret E, Boudeau J, Colombel J F. et al . Genetically related Escherichia coli strains associated with Crohn's disease.  Gut. 2001;  48 320-325
  • 9 Andersson R E, Olaison G, Tysk C, Ekbom A. Appendectomy and protection against ulcerative colitis.  N Engl J Med. 2001;  344 808-814
  • 10 Jarnerot G, Andersson M, Franzen L. Laparoscopic appendectomy in patients with refractory ulcerative colitis.  Gastroenterology. 2001;  120 1562-1563
  • 11 Bernstein C N, Blanchard J F, Rawsthorne P, Yu N. The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study.  Am J Gastroenterol. 2001;  96 1116-1122
  • 12 Grandval P, Barthet M, Desjeux A. et al . Pseudotumorous chronic pancreatitis associated with inflammatory bowel disease.  Dig Dis Sci. 2001;  46 898-900
  • 13 Terashima S, Hoshino Y, Kanzaki N. et al . Ulcerative duodenitis accompanying ulcerative colitis.  J Clin Gastroenterol. 2001;  32 172-175
  • 14 Bitton A, Peppercorn M A, Antonioli D A. et al . Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis.  Gastroenterology. 2001;  120 13-20
  • 15 Vermeire S, Joossens S, Peeters M. et al . Comparative study of ASCA (anti-Saccharomyces cerevisiae antibody) assays in inflammatory bowel disease.  Gastroenterology. 2001;  120 827-833
  • 16 Dubinsky M C, Ofman J J, Urman M. et al . Clinical utility of serodiagnostic testing in suspected pediatric inflammatory bowel disease.  Am J Gastroenterol. 2001;  96 758-765
  • 17 Umschaden H W, Szolar D, Gasser J. et al . Small-bowel disease: comparison of MR enteroclysis images with conventional enteroclysis and surgical findings.  Radiology. 2000;  215 717-725
  • 18 Beets-Tan R G, Beets G L, van der Hoop A G. et al . Preoperative MR imaging of anal fistulas: does it really help the surgeon?.  Radiology. 2001;  218 75-84
  • 19 D'Arienzo A, Scaglione G, Bennato R. et al . The prognostic value, in active ulcerative colitis, of an increased intensity of colonic perivisceral fat signal on magnetic resonance imaging with ferumoxsil.  Am J Gastroenterol. 2001;  96 481-486
  • 20 Bezabeh T, Somorjai R L, Smith I C. et al . The use of 1H magnetic resonance spectroscopy in inflammatory bowel diseases: distinguishing ulcerative colitis from Crohn's disease.  Am J Gastroenterol. 2001;  96 442-448
  • 21 Maunoury V, Mordon S, Geboes K. et al . Early vascular changes in Crohn's disease: an endoscopic fluorescence study.  Endoscopy. 2000;  32 700-705
  • 22 Matsuhashi N, Nakajima A, Suzuki A. et al . Long-term outcome of non-surgical strictureplasty using metallic stents for intestinal strictures in Crohn's disease.  Gastrointest Endosc. 2000;  51 343-345
  • 23 Perez-Cuadrado E, Molina P erez. Multiple strictures in jejunal Crohn's disease: push enteroscopy dilation.  Endoscopy. 2001;  33 194
  • 24 Esaki M, Matsumoto T, Hizawa K. et al . Intraoperative enteroscopy detects more lesions but is not predictive of postoperative recurrence in Crohn's disease.  Surg Endosc. 2001;  15 455-459
  • 25 Rajan E, Herman L J, Sorbi D. et al . Topical formalin therapy by means of an endoscopic applicator for control of ileoanal pouch ulcer bleeding.  Gastrointest Endosc. 2000;  52 422-424
  • 26 Charron M, di Lorenzo C, Kocoshis S. Are 99mTc leukocyte scintigraphy and SBFT studies useful in children suspected of having inflammatory bowel disease?.  Am J Gastroenterol. 2000;  95 1208-1212
  • 27 Alberini J L, Badran A, Freneaux E. et al . Technetium-99m HMPAO-labeled leukocyte imaging compared with endoscopy, ultrasonography, and contrast radiology in children with inflammatory bowel disease.  J Pediatr Gastroenterol Nutr. 2001;  32 278-286
  • 28 Eaden J A, Abrams K R, Mayberry J F. The risk of colorectal cancer in ulcerative colitis: a meta-analysis.  Gut. 2001;  48 526-535
  • 29 Bernstein C N, Blanchard J F, Kliewer E, Wajda A. Cancer risk in patients with inflammatory bowel disease: a population-based study.  Cancer. 2001;  91 854-862
  • 30 Askling J, Dickman P W, Karlen P. et al . Family history as a risk factor for colorectal cancer in inflammatory bowel disease.  Gastroenterology. 2001;  120 1356-1362
  • 31 Askling J, Dickman P W, Karlen P. et al . Colorectal cancer rates among first-degree relatives of patients with inflammatory bowel disease: a population-based cohort study.  Lancet. 2001;  357 262-266
  • 32 Heuschen U A, Hinz U, Allemeyer E H. et al . Backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitis.  Gastroenterology. 2001;  120 841-847
  • 33 Eaden J A, Ward B A, Mayberry J F. How gastroenterologists screen for colonic cancer in ulcerative colitis: an analysis of performance.  Gastrointest Endosc. 2000;  51 123-128
  • 34 Hanauer S B. Surveying surveillance: are gastroenterologists consistently inconsistent, inconsistently consistent, or poorly educated?.  Gastrointest Endosc. 2000;  51 240-242
  • 35 Friedman S, Rubin P H, Bodian C. et al . Screening and surveillance colonoscopy in chronic Crohn's colitis.  Gastroenterology. 2001;  120 820-826
  • 36 Cosnes J, Beaugerie L, Carbonnel F, Gendre J P. Smoking cessation and the course of Crohn's disease: an intervention study.  Gastroenterology. 2001;  120 1093-1099
  • 37 Hilsden R J, Hodgins D, Czechowsky D. et al . Attitudes toward smoking and smoking behaviors of patients with Crohn's disease.  Am J Gastroenterol. 2001;  96 1849-1853
  • 38 Ricart E, Panaccione R, Loftus E V. et al . Infliximab for Crohn's disease in clinical practice at the Mayo Clinic: the first 100 patients.  Am J Gastroenterol. 2001;  96 722-729
  • 39 Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease.  Gut. 2001;  48 642-646
  • 40 Dubinsky M. Idiosyncratic adverse reactions to 6-mercaptopurine and azathioprine can be averted by switching to thioguanine (6-TG) in patients with IBD [abstract].  Gastroenterology. 2001;  56 A12
  • 41 Colombel J F, Ferrari N, Debuysere H. et al . Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.  Gastroenterology. 2000;  118 1025-1030
  • 42 Rajapakse R O, Korelitz B I, Zlatanic J. et al . Outcome of pregnancies when fathers are treated with 6-mercaptopurine for inflammatory bowel disease.  Am J Gastroenterol. 2000;  95 684-688
  • 43 Gionchetti P, Rizzello F, Venturi A. et al . Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial.  Gastroenterology. 2000;  119 305-309
  • 44 Shanahan F. Probiotics in inflammatory bowel disease.  Gut. 2001;  48 609
  • 45 Steidler L, Hans W, Schotte L. et al . Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.  Science. 2000;  289 1352-1355
  • 46 Haderslev K V, Tjellesen L, Sorensen H A, Staun M. Alendronate increases lumbar spine bone mineral density in patients with Crohn's disease.  Gastroenterology. 2000;  119 639-646
  • 47 Milsom J, Hammerhofer K, Bohm B. et al . Prospective, randomized trial comparing laparoscopic vs. conventional surgery for refractory ileocolic Crohn's disease.  Dis Colon Rectum. 2001;  44 1-9
  • 48 Young-Fadok T M, Hall-Long K, McConnell E J. et al . Advantages of laparoscopic resection for ileocolic Crohn's disease.  Surg Endosc. 2001;  15 450-454
  • 49 Tichansky D, Cagir B, Yoo E. et al . Strictureplasty for Crohn's disease: meta-analysis.  Dis Colon Rectum. 2000;  43 911-919
  • 50 Regimbeau J M, Panis Y, Pocard M. et al . Long-term results of ileal pouch-anal anastomosis for colorectal Crohn's disease.  Dis Colon Rectum. 2001;  44 769-778
  • 51 Yu C S, Pemberton J H, Larson D. Ileal pouch-anal anastomosis in patients with indeterminate colitis: long-term results.  Dis Colon Rectum. 2000;  43 1487-1496

P. Marteau, M.D.

Service d'Hépato-Gastroenterologie · Hôpital Européen Georges Pompidou

20, rue Leblanc · 759 Paris Cédex 15 · France

Fax: + 33-1-56 09 35 54

Email: philippe.marteau@egp.ap-hop-paris.fr

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