Semin Neurol 2003; 23(2): 121-132
DOI: 10.1055/s-2003-41139
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Basic Principles of Immunotherapy for Neurologic Diseases

Reinhard Hohlfeld1 , Marinos C. Dalakas2
  • 1Institute for Clinical Neuroimmunology, Ludwig-Maximilians University Munich, Munich, Germany
  • 2Neuromuscular Diseases Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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Publication History

Publication Date:
01 August 2003 (online)

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ABSTRACT

Immunosuppressive drugs and immunomodulating procedures can improve the quality of life in patients with immune-related neurologic diseases and can even be lifesaving if properly used to avoid deleterious or irreversible adverse effects. For the successful use of these drugs or procedures, the treating physician must be familiar and comfortable with the drugs' mode of action, the accuracy of the diagnosis, the goals and expectations of therapy, and the risk-benefit ratio of the therapy. Improvement must be based on a beneficial change in activities of daily living and not solely on a change in the laboratory test values.

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